TIMI (Thrombolysis in Myocardial Infraction) flow grade in ST Elevation Myocardial Infarction after Primary Percutaneous Intervention
Abstract
Background: Timely reperfusion, preferably by primary percutaneous
intervention (PCI) has been the guiding-principle for the treatment of
patients with acute ST-elevation myocardial infarction (STEMI). TIMI
flow grade of the culprit lesion after the procedure have shown to have
significant implication in clinical outcome.
Objective: We aimed to study the relation of TIMI flow grade with the inhospital
outcome and complication among patients of STEMI.
Methods: All consecutive acute STEMI patients undergoing primary PCI
during the study period (January 2020 to June 2020) were analyzed for
correlation between TIMI flow grade and clinical outcome during the
hospital stay. Prior approval was taken from institutional review board.
The study design was retrospective observational study.
Result: 51(55%) patients had achieved the TIMI 3 flow after the primary
PCI. Number of patients achieving TIMI flow of 2,1 and 0 after the
procedure were 34(37%),6(6.5%) and 2(2%). Incidence of traditional risk
factors like dyslipidemia, diabetes, hypertension was higher in TIMI flow
<2 . TIMI flow <2 was also associated with more adverse events namely
cardiogenic shock, arrythmias, in-hospital mortality and overall major
adverse cardiovascular events.
Conclusion: Patients with dyslipidemia had poor TIMI flow grade during
primary PCI. Similarly, patients having hypertension, diabetes mellitus and
late presentation showed tendency for TIMI flow <2 . Also, the poor TIMI
flow grade after primary PCI had unfavorable the clinical outcomes like
increased complications and mortality.
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