Squamous Cell Carcinoma Arising in a Mature Cystic Teratoma of the Ovary: A Case Report

  • Poonam Lama Paropakar Maternity and Women’s Hospital, National Academy for Medical Sciences, Kathmandu, Nepal
  • Jitendra Pariyar Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Bimal Kumar Thapa Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Neer Shobha Chitrakar Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Isha Shrestha Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Rima Maharjan Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Arun Prasad Joshi Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Pabitra Maharjan Gynecology Department, Civil Service Hospital, Kathmandu, Nepal
  • Sammer Neupane Pathology Department, Civil Service Hospital, Kathmandu, Nepal
  • Srijana Koirala Pathology Department, Civil Service Hospital, Kathmandu, Nepal
  • Pratit Poudel Radiology Department, Civil Service Hospital, Kathmandu, Nepal
Keywords: dermoid, malignant transformation, mature cystic teratoma, squamous cell carcinoma

Abstract

Mature cystic teratomas account for about 30-45% of all ovarian tumors. Malignant transformation in these tumors is a rare event, occurring in only 0.17-2% of cases, with squamous cell carcinoma
being the most common type. As there are no specifi c signs and symptoms to suggest malignancy in dermoid cyst, it is diffi cult to predict, and most cases are diagnosed postoperatively. We report
a 55-year-old postmenopausal lady who presented with the complaint of pain in abdomen and abdominal distension for four months and a large complex abdomino-pelvic mass evident clinically and radiologically. Final histopathology was reported as malignant transformation in mature cystic teratoma. The patient was assigned to squamous cell carcinoma of the ovary arising in a mature cystic teratoma, surgical stage IIC. In view of the poor prognosis, adjuvant chemotherapy was given.

Published
2019-12-02