Squamous Cell Carcinoma in Non-Functioning Kidney Associated with Staghorn Calculi: Uncommon Presentation of Common Malignancy

Abstract

Cancers of the kidney account for 2% of all the total human cancer. Squamous cell carcinoma (SCC) of renal
pelvis is a rare neoplasm, accounting for only 0.5 to 0.8% of malignant renal tumors. In most cases, renal SCC is
associated with chronic infections, chronic renal calculi, radiotherapy or any factor that can irritate the urothelium.
We report a female patient aged 60 years diagnosed with Right Non-functioning Kidney with Nephrolithiasis with
Suspicious Mass. Histopathological diagnosis with Squamous Cell Carcinoma in Stage III with Staghorn Calculi. In
long standing urolithiasis, possibility of concomitant harboring of malignancy needs to be taken into consideration.