Paudyal, B2023-06-052026-06-162023-06-052026-06-162010PaudyalB. (2010). Antiphospholipid Sundrome in Childhood Systemic Lupus Erythematosus. Journal of Nepal Health Research Council. https://doi.org/10.33314/jnhrc.v0i0.226Print ISSN: 1727-5482; Online ISSN: 1999-6217https://hdl.handle.net/20.500.14572/6593Antiphospholipid syndrome is an autoimmune disease that presents with recurrent arteriovenous thrombosis, repeated pregnancy loss and elevated titres of anti phospholipid antibodies in the blood. It is a common cause of acquired thrombosis and can manifest within any part of the vascular tree. Inferior Venacava thrombosis at outset, however, is not a common manifestation of systemic lupus erythematosus associated- antiphospholipid syndrome particularly in children. Here, we present a 14-year old girl who developed antiphospholipid syndrome as a presenting manifestation of systemic lupus erythematosus. Â Key words: antiphospholipid syndrome, thrombosis, systemic lupus erythematosusenAntiphospholipid syndromeThrombosisSystemic lupus erythematosusArticle