Shrestha, Sushan ManShrestha, Samir2025-07-252025-07-252024https://hdl.handle.net/20.500.14572/644Sushan Man Shrestha Central Department of Public Health, Institute of Medicine, Tribhuvan University Samir Shrestha Central Department of Public Health, Institute of Medicine, Tribhuvan UniversityAbstract Introduction: The infertility problem is one of the growing public health issues in Nepal and the anxiety and depression related to this problem is not much studied. Objective: The aim of this study is to find status of anxiety and depression among the reproductive aged women having fertility problem and its associated factors. Methods: A cross-sectional comparative study was conducted with a sample size of 177 respondents. Hospital Anxiety and Depression Scale was used to access the anxiety and depression of the respondents. Chi Squared test and multivariate logistic regression was applied to find the association of anxiety and depression with socio-demographic, personal and health related variables. Results: The status of no, mild, moderate and severe anxiety were 52.7%, 24.2%, 17.6% and 5.5% respectively in fertile group and 30.2%, 23.3%, 14.0% and 32.6% in infertile group. Similarly, the status of no, mild, moderate and severe depression were 64.8%, 29.7%, 4.4% and 1.1% in fertile group and 50.0%, 14.0%, 8.1% and 27.9% in infertile group respectively. Both anxiety and depression were found to be statistically significant between fertile and infertile groups. Occupation [AOR 0.407 (0.203-0.817)], perceived income stress [2.124 (1.062-4.249)] and fertility status [2.463(1.254-4.838)] for anxiety and difficulties in relationship between couple [8.216(2.365-28.548)] for depression was found to be statistically significant. Conclusions: This study revealed fertility status, occupation status, and perceived income stress as the factors associated to anxiety and difficulties in relationship between couple as the factor associated with depression. Keywords: Keywords: Infertility, anxiety, depressionen-USArticle