Nepal, RichaSapkota, KalyanGurung, SantoshPaudel, PramodNeupane, PrateekSah, Kamlesh Kumar2026-03-252026-03-252020https://hdl.handle.net/20.500.14572/5398Richa Nepal Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, Nepal https://orcid.org/0000-0001-7576-2593 Kalyan Sapkota Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, Nepal https://orcid.org/0000-0003-4011-6430 Santosh Gurung Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, Nepal https://orcid.org/0000-0002-1069-8030 Pramod Paudel Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, Nepal Prateek Neupane Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, Nepal Kamlesh Kumar Sah Department of Internal Medicine, Bharatpur Hospital, Bharatpur, Province-3, Chitwan, NepalAbstract: Recurrent or persistent positivity of SARS-CoV-2 RNA in clinically recovered COVID-19 patients have been reported worldwide. However, replication competent live viruses were not recovered beyond two to three weeks from onset of symptoms in mild to severe cases of COVID-19. End stage renal disease is characterized by uremia induced immune dysfunction that increases the risk of infectious diseases including COVID-19. The clinical implications of recurrent or persistently positive SARS-CoV-2 RNA in immunocompromised patients are difficult to be generalized to findings as in immunocompetent patients. We report a case of end stage renal disease with recent history of recovered COVID-19 pneumonia, who again presented with positive reverse transcriptase- polymerase chain reaction (RT-PCR) test for SARS-CoV-2 RNA.en-UScoronavirus diseaseCOVID-19end-stage kidney diseasesevere acute respiratory syndrome coronavirus-2Article