Khatiwoda, PKayastha, SRKhatiwada, PGiri, ABaral, SBista, DPant, P2025-08-252025-08-252012https://hdl.handle.net/20.500.14572/2005Khatiwoda P,1 Kayastha SR,2 Khatiwada P,1,2 Giri A,1,2 Baral S,2 Bista D,1,2 Pant P1,2 1Richa Bajimaya Memorial Foundation 2Kathmandu University School of Medical Sciences (KUSMS)ABSTRACT Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. We present a 40-year-old male who presented with four months history of generalized skin lesion, pain and weakness. He had elevated transaminases with detectable muscle weakness. This case highlights the need to consider dermatomyositis with skin lesion and weakness; and the use of aggressive immunosuppressive therapies due to its associated vasculopathies. KEY WORDS Cutaneous lesions, dermatomyositis, idiopathic, myopathy, vasculitisen-USArticle