Kumar, Mani KantPatel, Pankaj KumarTahir, Mohammad Mahtab Ali2026-05-252026-05-252012https://hdl.handle.net/20.500.14572/6240Mani Kant Kumar Assistant Professor, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar Pankaj Kumar Patel Assistant Professor, Department of Pathology, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar Mohammad Mahtab Ali Tahir Junior Resident, Department of Paediatrics, Narayan Medical College and Hospital, Jamuhar, Sasaram, BiharAbstract: Bruton’s X-Linked Agammaglobulinemia (XLA) is an X linked recessive primary immune deficiency disorder characterized by recurrent bacterial infections and failure to generate immunoglobulins of all isotypes due to the absence or profoundly decreased mature B cells and plasma cells, secondary to mutations in the Bruton’s tyrosine kinase (Btk) gene. The coexistence of chronic monoarticular arthritis in a patient with Bruton’s XLA has been described an uncommon presentation. We describe a 5 year-old boy with XLA and chronic monoarticular arthritis.en-USBruton’s X-linked AgammaglobulinemiaChronic monoarticular arthritisBtk geneArticle