Shrestha, P NDas, ARayamajhi, AMahaseth, C2026-05-212026-05-212012https://hdl.handle.net/20.500.14572/6166P N Shrestha Kanti children hospital, Maharajgunj, Kathmandu, Nepal A Das Kanti children hospital, Maharajgunj, Kathmandu, Nepal A. Rayamajhi Kanti children hospital, Maharajgunj, Kathmandu, Nepal C Mahaseth Kanti children hospital, Maharajgunj, Kathmandu, NepalAbstract Introduction: Rheumatic fever and rheumatic heart disease is a common problem in developing countries. Rheumatic valvular heart disease is one of the important risk factor for infective endocarditis. Methods: Retrospective study was conducted among 56 children admitted in cardiology ward of Kanti children hospital with the diagnosis of rheumatic fever or rheumatic heart disease during May 2008 to M ay 2010. Results: We found male to female ratio 2: 1, median age 12 (5- 14yrs) with the most affected age group of 11- 12 years. Common symptoms were fever (66%), dyspnea (68%), joint pain (50%), palpitation (30%), cough (16%) and chest pain (12%). Only 9% of patients had positive history of sore throat. Six ty percent patients were presented with features of congestive cardiac failure (CCF). A SO positive was found in 25 (44.6%) cases. The most common valvular lesion was mitral regurgitation (M R). Moderate to severe mitral regurgitation was found in 89% of cases. Tricuspid regurgitation (T R) was found in 57% of patients and aortic regurgitation (A R) in 55% of cases. Thirty-two patients (57%} had PA H in which 8 patients has severe PAH and 24 patients had mild to moderate PAH . Infective endocarditis was diagnosed in twenty patients (35.7%). Out of 20 patients 14 (70%) had vegetation in echocardiography. The mortality was 11% in this study. Conclusion: Infective endocarditis is the major complication of rheumatic heart disease among children of Nepal and so clinical suspecian is important whenever patients with rheumatic heart disease present with fever. Keywords: dyspnea, endocarditis, rheumatic fever, rheumtic heart diseaseen-USdyspneaendocarditisrheumatic feverrheumtic heart diseaseArticle