Hamal, BhadraKarmacharya, MaheshBhattachan, SijanHamal, Pawan Kumar2025-07-222025-07-222024https://hdl.handle.net/20.500.14572/532Bhadra Hamal National Academy of Medical Sciences, National Trauma Center, Kathmandu, Nepal Mahesh Karmacharya National Academy of Medical Sciences, National Trauma Center, Kathmandu, Nepal Sijan Bhattachan National Academy of Medical Sciences, National Trauma Center, Kathmandu, Nepal Pawan Kumar Hamal National Academy of Medical Sciences, National Trauma Center, Kathmandu, NepalBackground: Multi-ligament injuries of the knee are rare injuries that can cause significant impairment of the knee function. There is controversy in the treatment regarding staged versus single-stage surgery. This study was performed to assess the outcome of the single-staged reconstruction of the multi-ligament injury of the knee. Methods: This prospective observational study was done from January 15, 2022 to January 14, 2023. The outcome was analyzed by comparing the preoperative and 12-month postoperative Visual Analog Scale score, Lysholm Score, and International Knee Documentation Committee Score. Results: The mean age of the patients was 28.35 years. among 12 patients 9 were male and 3 were female. Single-staged multi-ligament reconstruction was done in all the cases. The Lysholm score was improved from preoperatively 36.42 ± 1.46 to 95.36 ± 2.84, IKDC score was improved from 24.38 ± 1.64 to 93.86 ± 3.14, VAS score 8.14 ± 1.44 to 0.40 ± 0.60 at 12 months postoperative follow-up which all came to be clinically significant with p-value < 0.001. Conclusions: Single-stage multi-ligament reconstruction of the knee is an effective method of treatment and has excellent outcomes. Keywords: Multi-ligament injury; reconstruction; single-stage.en-USArticle