Paudyal, SanjayaShah, SurendraGiri, Niraj2024-03-242024-03-242022NepalY. J., PaudyalS., ShahS., & GiriN. (2023). Laparoscopic Appendectomy versus Open Appendectomy in Acute Appendicitis. Journal of Nepal Health Research Council, 20(4), 825-829.Print ISSN: 1727-5482; Online ISSN: 1999-6217https://hdl.handle.net/20.500.14572/47Original ArticleAbstract Background: Appendectomy is the most common emergency surgical procedure performed. Appendectomy is performed by either open or laparoscopic methods. However, there is lack of consensus regarding the most appropriate method. This study aimed to compare the outcomes of laparoscopic and open appendectomy in the treatment of acute appendicitis. Methods: Fifty-two patients undergoing appendectomy were analyzed in this prospective comparative study, with 26 patients each in laparoscopic and open group. The outcomes were measured in terms of operative time, postoperative pain at 4, 6 and 12 hours, length of hospital stay, postoperative complications according to modified Clavien Dindo classification and cost analysis. Results: Laparoscopic group had longer time after completion of surgery till exit from operation theatre (30 min in laparoscopic and 20 min in open, p<0.01) and significantly higher cost (Nrs. 26295 for laparoscopic and Nrs. 19575 for open, p<0.01) than open appendectomy. Operative time, time from entering operation theatre till being kept in operation table, time from being kept in operation table till initiation of anesthesia, postoperative pain at 4,6 and 12 hours and postoperative complications were insignificant in both groups. Conclusions: The results suggest that laparoscopic appendectomy group had longer recovery time after operation and was costlier than open appendectomy. Thus, the decision of the operative procedure can be based on the patient’s preference. Keywords: Appendectomy; laparoscopic appendectomy; open appendectomyenAppendectomyLaparoscopic appendectomyOpen appendectomyJournal Article