Srivastava, VKAgrawal, SAhmed, MSharma, S2025-10-072025-10-072015https://hdl.handle.net/20.500.14572/2474Srivastava VK,1 Agrawal S,2 Ahmed M,1 Sharma S1 1Apollo Hospitals Bilaspur, Chhattisgarh, India 2Himalayan Institute of Medical Sciences, Dehradun, IndiaABSTRACT Myasthenia gravis is a disease of great challenge to the anesthesiologist, because it affects the neuromuscular junction. Anesthetic management involves either muscle relaxant or non-muscle relaxant techniques. This case report documents the safe use of fentanyl, propofol and sevoflurane combination guided by bispectral index, without the use of muscle relaxants in a patient with myasthenia gravis who presented for meningioma surgery. KEY WORDS Fentanyl, myasthenia gravis, propofol, sevofluraneen-USFentanylMyasthenia gravisPropofolSevofluraneArticle