Jain, Sonia PSonkusale, PratikshaDeshmukh, Abhay VilasKumari, Pallavi2025-09-232025-09-232021https://hdl.handle.net/20.500.14572/2280Sonia P Jain Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India https://orcid.org/0000-0002-3376-2250 Pratiksha Sonkusale Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India Abhay Vilas Deshmukh Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India Pallavi Kumari Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, IndiaAbstract: Acrokeratosis verruciformis of Hopf (AKV) is a rare autosomal dominant genodermatosis of unknown etiology. Here we present a case of a 20-year-female with multiple skin-colored flat papules over the dorsum of hands and feet interspersed with multiple hypopigmented macular lesions of 5 years duration. No family member showed a similar lesion. The presence of classical AKV with absent family history and definite histopathology findings make this case an unusual and rare entity.en-USAcrokeratosis verruciformis of HopfGenodermatosisHypopigmented maculesArticle