Singh, YogendraVaidya, PradeepShrestha, UttamSayami, GeetaKumar, AnilKhakurel, Mahesh2026-07-222026-07-221999https://hdl.handle.net/20.500.14572/7025Yogendra Singh Department of Surgery, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Pradeep Vaidya Department of Surgery, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Uttam Shrestha Department of Surgery, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Geeta Sayami Department of Pathology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Anil Kumar Department of Surgery, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Prof. Mahesh Khakurel Department of Surgery, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, NepalAbstract A 32-year-old male with a low grade non-Hodgkin's lymphoma (NHL) of the ascending colon presented 5 years after the successful treatment of Hodgkin's disease HD). According to the literature, the occurrence of a second primary cancer is a great problem in the survivors of HD, which is the result of immunosuppression due to the disease itself or following chemotherapy and/or radiotherapy for it. Therefore, patients with HD must be followed-up regularly and for lifelong. Keywords: Second cancer, Hodgkin's disease, Chemotherapy, Follow-upen-USSecond cancerHodgkin's diseaseChemotherapyFollow-upArticle