Gyawali, SiddinathPokhrel, BirajSharma, DeepakBhatta, Naveen ChandraKandel, Bishnu PrasadLakhey, Paleswan Joshi2025-10-192025-10-192023https://hdl.handle.net/20.500.14572/2802Siddinath Gyawali Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal Biraj Pokhrel Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal Deepak Sharma Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal Naveen Chandra Bhatta Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal Bishnu Prasad Kandel Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal Paleswan Joshi Lakhey Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, NepalAbstract The adenosquamous carcinoma of the gallbladder is a rare variant accounting for only 1-4% of all primary gallbladder carcinoma. Regardless of the histological types, all gallbladder carcinomas have silent and rapid progression resulting in delayed diagnosis and poor prognosis. Even with medical and/or surgical interventions, the median survival of patients with adenosquamous carcinoma, one of the histological variants, is less than a year. However, we present a case of adenosquamous carcinoma with an unusually better prognosis. A 70-year-old female patient, after being diagnosed with gallbladder carcinoma was suggested for surgical resection but was lost to follow-up since then. Two years later, the patient presented and was managed with extended cholecystectomy. The slow progression and non-recurrence of the tumour during follow-up for two years after the surgery indicates a better prognosis in this case.en-USCarcinomaCase reportsCholecystectomyPrognosisOther