Sitaula, Ranju KharelManandhar, UmangLama, Dichen Meghna2026-02-082026-02-082025https://hdl.handle.net/20.500.14572/4589Ranju Kharel Sitaula, Umang Manandhar, Dichen Meghna Lama Department of Ophthalmology, Maharajgunj Medical Campus, B.P. Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Kathmandu, NepalABSTRACT Ocular involvement in Buerger’s disease is rare, with acute anterior uveitis (AAU) and hyphema being uncommon manifestations. We report a case of a 40-year-old male with Buerger’s disease presenting with AAU and hyphema. The patient presented with sudden onset redness and pain in the right eye for 3 days, with 1 mm hyphema and fibrin deposits. He had a history of peripheral vasculopathy and multiple amputations. Ocular exam revealed non-granulomatous acute anterior uveitis with hyphema. Vision and inflammation improved within 2 days of treatment. Hyphemic acute anterior uveitis can occur in Buerger’s disease, and early management is crucial to prevent progression. Keywords: Buerger’s disease; hyphema; red eye; uveitisen-USBuerger’s diseasehyphemared eyeuveitisArticle