Singh, ABairy, I2026-07-082026-07-082005https://hdl.handle.net/20.500.14572/6897A. Singh Department of Clinical Microbiology, Kasturba Medical, Manipal I Bairy Department of Clinical Microbiology, Kasturba Medical, ManipalAbstract Background: Cryptosporidium parvum a coccidian protozoal parasite causes a protracted lifethreatening diarrhea in HIV sero-positive patients. This study was conducted to find out distribution of cryptosporidium infection in HIV sero-positive patients (with acute or chronic diarrhea) admitted in Kasturba Hospital, Manipal, South India. Method: Freshly passed stool samples were collected and stained with modified Ziehl Neelson staining technique and examined under microscope for the detection of oocyst of Cryptosporidium. Results: Thirty out of 70 (42.85%) of HIV sero-positive patients were found to have Cryptosporidium parvum oocyst in their stool samples. Conclusion: Known prevalence of cryptosporidial in HIV positive patients can help in starting prophylaxis and can significantly reduce morbidity and mortality associated with severe diarrhea.en-USArticle