Mahato, Arun KumarShrestha, NischalGharti, Sakar BabuShah, Madhu2025-12-072025-12-072022https://hdl.handle.net/20.500.14572/3421Arun Kumar Mahato Department of Internal Medicine, Nobel Medical College Teaching Hospital, Biratnagar, Morang, Nepal https://orcid.org/0000-0001-6224-7226 Nischal Shrestha Department of Internal Medicine, Nobel Medical College Teaching Hospital, Biratnagar, Morang, Nepal https://orcid.org/0000-0002-1118-3039 Sakar Babu Gharti Department of Internal Medicine, Nobel Medical College Teaching Hospital, Biratnagar, Morang, Nepal Madhu Shah Department of Pediatrics, Nobel Medical College Teaching Hospital, Biratnagar, Morang, NepalAbstract Introduction: Dengue and typhoid fever are different entities with overlapping signs and symptoms which are indistinguishable and there have been few reports of co-infections from endemic areas. The resemblance of symptoms makes accurate clinical diagnosis and treatment difficult. Both are major health problems mainly during monsoon and co-infection, if not timely diagnosed and treated can be fatal. The aim of this study was to find out the prevalence of typhoid fever among patients diagnosed with dengue at a tertiary care centre. Methods: A descriptive cross-sectional study was done among patients of age >15 years with dengue fever attending the medicine outpatient department in a tertiary care centre from 1 July 2021 to 30 June 2022. Ethical approval was taken from the Institutional Review Committee (Reference number: 466/2020). Convenience sampling was used. Patients with other risk factors for febrile illness were excluded from the study. Point estimate and 90% Confidence Interval were calculated. Results: Among 95 dengue cases, typhoid fever was observed in 18 (18.95%) (12.36-25.54, 90% Confidence Interval). The mean age of presentation was 35±9 years with a male to female ratio of 0.8:1. Fever was the most common presentation with a mean temperature of 100.8±2.1°F. Conclusions: The prevalence of typhoid fever among dengue-positive cases was higher as compared to other studies done in similar settings.en-USDengueFeverTyphoid feverArticle