Jhunjhunwala, Adarsh KumarMagar, Dilasma GhartiUpreti, DipeshThapa, NikuGhosh, ArnabThapa, SushmaRegmi, SudeepTimilsina, Bishowdeep2026-01-182026-01-182022https://hdl.handle.net/20.500.14572/4307Adarsh Kumar Jhunjhunwala Department of Pathology, Manipal College of Medical Sciences, Pokhara, Kaski, Nepal https://orcid.org/0000-0001-5501-5849 Dilasma Gharti Magar Department of Pathology, Manipal College of Medical Sciences, Pokhara, Kaski, Nepal Dipesh Upreti Manipal College of Medical Sciences, Pokhara, Kaski, Nepal Niku Thapa Manipal College of Medical Sciences, Pokhara, Kaski, Nepal Arnab Ghosh Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal Sushma Thapa Department of Pathology, Manipal College of Medical Sciences, Pokhara, Kaski, Nepal Sudeep Regmi Department of Pathology, Manipal College of Medical Sciences, Pokhara, Kaski, Nepal Bishowdeep Timilsina Department of Surgery, Manipal College of Medical Sciences, Pokhara, Kaski, NepalAbstract Primary mucinous carcinoma of the skin is a rare malignant neoplasm showing predilection to the periorbital region. These tumours are indolent and low-grade, with a tendency for local, sometimes multiple, recurrences. Distinguishing between these primary neoplasms and the more frequent metastatic mucinous deposits on the skin from primaries in the breast and gastrointestinal tract constitutes a diagnostic dilemma. In this case report, we have put forth the findings of a 70-year-old male who presented with a slow-growing periorbital swelling and was subsequently diagnosed with mucinous adenocarcinoma. An extensive workup in search of another primary tumour failed to show a primary malignancy elsewhere and the diagnosis of primary mucinous adenocarcinoma of the skin was rendered.en-USCase reportsMucinous carcinomaNepalSialomucinsOther