Bhattarai, PShrestha, PN2026-06-182026-06-182008https://hdl.handle.net/20.500.14572/6686P. Bhattarai Nepalgunj Medical College, Kanti Children’s Hospital, Department of Child Health, Institute of Medicine, Kathmandu, Nepal P.N. Shrestha Nepalgunj Medical College, Kanti Children’s Hospital, Department of Child Health, Institute of Medicine, Kathmandu, NepalAbstract Background: Guillain-Barré Syndrome (GBS) is a group of autoimmune syndromes consisting ofdemyelinating and acute axonal degenerating forms of the disease. This study gives the profile of 30patients who were admitted with the diagnosis of GBS in a pediatric hospital. Methods and material: We reviewed the admitted case notes of children admitted with the diagnosisof GB syndrome from January 2005 to December 2007. The data were analyzed to find out thedemographic features, preceding illness, clinical features and CSF findings. Result: The age ranged from 3.6 years to 14 years. The mean (SD) age was 4.9 (9.7) years. The mostcommon symptoms were inability to walk after awaking in the morning.The median evolving time from the onset of illness to nadir was 12 days. The CSF protein concentrationranged from 60 to <100mg% and the CSF cell counts were less than 10/cmm in 23 patients and 11-19in 7 patients. Conclusion: We could not find any previous study done in such a large paediatric population of thiscountry. Our results show the similarity in pattern of age distribution, preceding events, and cellprotein dissociation similar to that of other studies. Keywords: Guillain-Barré Syndrome, diagnostic criteria, children, clinical profile, hospitalen-USGuillain-Barré Syndromediagnostic criteriachildrenclinical profilehospitalArticle