Prasai, ParikshitJoshi, AnjaliPoudel, SantoshK.C., SarjanPahari, Rabin2025-10-162025-10-162023https://hdl.handle.net/20.500.14572/2754Parikshit Prasai Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Anjali Joshi Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Santosh Poudel Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Sarjan K.C. Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Rabin Pahari Department of Surgery, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, NepalAbstract Abdominal tuberculosis is defined as infection of gastrointestinal tract, peritoneum, abdominal solid organs, and/or abdominal lymphatics constituting approximately 12% of extra-pulmonary tuberculosis cases. Intestinal perforation is an acute presentation of abdominal tuberculosis. Intestinal perforation can occur before or at the beginning of anti-tubercular therapy. It is considered to be a paradoxical reaction if it occurs during or after treatment. Intestinal perforation is uncommon but serious and life-threatening as complication-mortality rate secondary to perforation are estimated to be >30%. We present a case of an 18-year-old female who developed cecal perforation following an intraperitoneal abscess after completion of anti-tubercular therapy for intestinal tuberculosis. She was a known case of intestinal tuberculosis. She had undergone pigtail catheterisation for an intraperitoneal abscess and completed 18 months of anti-tubercular therapy after which she developed cecal perforation. A paradoxical response was observed following the completion of anti-tubercular therapy. Early diagnosis and treatment reduce the complications and mortality rates of cecal perforation due to abdominal tuberculosis.en-USCase reportsCecumIntestinal perforationTuberculosisOther