Ghimire, GMagar, JKGBhattacharya, SMahapatra, TM2026-07-082026-07-082005https://hdl.handle.net/20.500.14572/6898G. Ghimire Department of Microbiology, B.P. Koirala Institute of Health and Sciences (BPKIHS), Dharan Nepal J.K.G MAGAR Department of Microbiology, B.P. Koirala Institute of Health and Sciences (BPKIHS), Dharan Nepal S. Bhattacharya Department of Microbiology, B.P. Koirala Institute of Health and Sciences (BPKIHS), Dharan Nepal T.M. Mahapatra Department of Microbiology, B.P. Koirala Institute of Health and Sciences (BPKIHS), Dharan NepalAbstract Acinetobacter spp. is ubiquitous, aerobic gram-negative coccobacilli that are now emerging as an important nosocomial pathogen. In our study over a period of one year (January 2002- December 2002) at BPKIHS, a tertiary care hospital, from a total no. of 1089 isolates from pus/ aspirates of ICU, Burns, Orthopedic and other post operative wards, 146 isolates (13.4%) were Acinetobacter spp. Out of 146, 23 isolates of Acinetobacter spp. were sensitive to base line drugs. Remaining 123 strains of Acinetobacterspp. were resistant to Cefotaxime (99.2%), Ceftazidime (98.4%), Tobramicin (95.9%), Amikacin (96.7%), Netilmicin (89.43%), Ciprofloxacin (96.7%). Apart from these antibiotics none of the strains were sensitive to Piperacillin.en-USAcinetobacter spc. : A major isolates of nosocomial infection’s – clinical significance and antimicrobial susceptibilityArticle