Kavthekar, Saiprasad OnkareshwarAmith, K.Kurane, Anil BapuraoPhulari, Yoganand J.2025-11-122025-11-122022https://hdl.handle.net/20.500.14572/3147Saiprasad Onkareshwar Kavthekar Department of Paediatrics, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India K. Amith Department of Paediatrics, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India Anil Bapurao Kurane Department of Paediatrics, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India. Yoganand J Phulari Department of Dermatology, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India.Abstract: Stevens Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are hyper sensitive life - threatening rare dermatological reactions. In SJS - TEN overlap syndrome, the extent and severity of epidermal detachment is 10- 30%. Drugs like sulfonamides, nonsteroidal anti- inflammatory agents, antibiotics and anticonvulsants are the commonest precipitants. Here, we present a rare case of SJS - TEN overlap syndrome in a previously normal 11 years old girl after acetaminophen intake for fever. This case report is intended to make paediatricians aware that the adverse reaction like SJS - TEN overlap syndrome can develop with a drug like acetaminophen which is supposed to be the safest antipyretic in paediatrics.en-USAcetaminophenChildToxic Epidermal NecrolysisSteven-Johnson SyndromeArticle