Phuyal, SubashPrabhakar, AnujBala, ParthibanGaikwad, Sailesh2026-08-142026-08-142020https://hdl.handle.net/20.500.14572/7299Subash Phuyal Department of Neuroimaging and Interventional Neuroradiology, AIIMS, New Delhi, India Anuj Prabhakar Department of Neuroimaging and Interventional Neuroradiology, AIIMS, New Delhi, India Parthiban Bala Department of Neuroimaging and Interventional Neuroradiology, AIIMS, New Delhi, India Sailesh Gaikwad Department of Neuroimaging and Interventional Neuroradiology, AIIMS, New Delhi, IndiaAbstract Intradural spinal epidermoid cysts are rare, benign lesions either acquired from trauma, surgery, lumbar puncture or arise as congenital lesions, particularly associated with spinal dysraphism. Epidermoid cyst arising from the spine with expansile destruction of vertebrae has not been reported yet in the literature. We report a case of 36-years male presented with history of fall 8 years back with progressive symptoms of lower back pain, weakness of left lower limb and bladder/bowel incontinence. Computed tomography revealed large lytic expansile, midline sacral vertebral lesion with soft tissue component and multiple calcific foci. Magnetic resonance imaging demonstrated large non-enhancing heterogeneous mass showing restricted diffusion on diffusion weighted images. The patient underwent biopsy confirming the diagnosis of an epidermoid cyst. The possibility of an epidermoid tumor should be kept in the differential diagnosis in patients presenting with post-traumatic sacral mass. Keywords: epidermoid cyst; intradural-extramedullary spinal cord neoplasms; restricted diffusion; spinal canal.en-USepidermoid cystintradural-extramedullary spinal cord neoplasmsrestricted diffusionspinal canalArticle