Sah, Kailash PrasadRai, Ganesh KumarShrestha, PNShrestha, Amit2026-06-052026-06-052010https://hdl.handle.net/20.500.14572/6375Kailash Prasad Sah Assistant Professor (NAMS) and Consultant Paediatric Oncologist, Kanti Children’s Hospital, Kathmandu Ganesh Kumar Rai Associate Professor (NAMS) and Senior Consultant Paediatrician, Kanti Children’s Hospital, Kathmandu PN Shrestha Assistant Professor (NAMS), Kanti Children’s Hospital, Kathmandu Amit Shrestha Clinical Hematologist, Kanti Children’s Hospital, KathmanduAbstract: Introduction: Wilm's tumor is the second most common abdominal tumor in children. It arises from the kidney. The survival of children with Wilm's tumor has improved over the past 25 years. Objectives: To study the clinical presentation of Wilm’s tumor and evaluate the ten year survival. Materials and Methods: A retrospective hospital based study was conducted at Kanti Children's Hospital from March 1998 to February 2008. A total of 60 histopathologically diagnosed children below 14 yr of age were included in the study. Results: About 2/3rd (66.5%) presented with abdominal swelling followed by abdominal pain (16.5%) and fever (13.5%). A few children manifested with red colored urine (3.5%). The age of children ranged from one month to 13 years with the mean age of 36 months. Males were affected more than the females (M:F=3:1). Most affected age group was 2 to 5 yrs (41.5%) followed by 1 to 2 yrs (25.0%). Most of the cases were in stage III (36.5%) followed by stage II (33.5%). SIOP protocol was used to treat these children and overall 10 year survival rate was 50.0%. One fifth (20%) of the cases died, 16.5% relapsed and 13.5% lost to follow up. Conclusion: Despite severe resource limitations, paediatric oncology unit at Kanti Children’s Hospital has been successfully treating Wilm's tumor with the success rate of 50.0%.en-USChemotherapyOutcomeRemissionWilm’s tumorSIOPArticle