Dangol, NixonBasnet, Ranga BahadurParajuli, SharmilaAmatya, Riti2026-07-092026-07-092015https://hdl.handle.net/20.500.14572/6918Nixon Dangol Department of Pathology, Kathmandu Model Hospital, Pradarsani marg, Kathmandu, Nepal https://orcid.org/0009-0001-2680-5830 Ranga Bahadur Basnet Department of Pathology, Kathmandu Model Hospital, Pradarsani marg, Kathmandu, Nepal Sharmila Parajuli Department of Pathology, Kathmandu Model Hospital, Pradarsani marg, Kathmandu, Nepal Riti Amatya Department of Pathology, Kathmandu Model Hospital, Pradarsani marg, Kathmandu, NepalAbstract: Granulomatous cholecystitis is a condition affecting the gallbladder that is often confused with cancers and other types of cholecystitis, which poses a diagnostic challenge for medical professionals. We share a case of granulomatous cholecystitis in a 51-year-old man with resolving acute pancreatitis and hypertension. Imaging showed thickening of the gallbladder wall and presence of gallstones. Laparoscopic cholecystectomy was performed and histopathological examination confirmed that the patient had granulomatous cholecystitis, characterized by presence of epithelioid histiocytes and multinucleated giant cells. The case highlights the importance of considering granulomatous cholecystitis in the differential diagnosis of gallbladder diseases, especially in patients presenting with chronic inflammation and gallstones. This report underscores the need for high clinical suspicion to differentiate granulomatous cholecystitis from other gallbladder pathologies.en-USChronic inflammationgallbladder granulomasgallbladder tuberculosisgranulomatous cholecystitisArticle