Kumar, JagadishChowdary, SatyeshVG, ManjunathDas, Sudha KiranVuyyuru, Manovihari2025-12-222025-12-222020https://hdl.handle.net/20.500.14572/3769Jagadish Kumar Department of Paediatrics, Jagadguru Sri Shivarathreeshwara Medical College, Jagadguru Sri Shivarathreeshwara University, Mysore, India Satyesh Chowdary Department of Paediatrics, Jagadguru Sri Shivarathreeshwara Medical College, Jagadguru Sri Shivarathreeshwara University, Mysore, India Manjunath VG Department of Paediatrics, Jagadguru Sri Shivarathreeshwara Medical College, Jagadguru Sri Shivarathreeshwara University, Mysore, India Sudha Kiran Das Department of Paediatrics, Jagadguru Sri Shivarathreeshwara Medical College, Jagadguru Sri Shivarathreeshwara University, Mysore, India Manovihari Vuyyuru Department of Paediatrics, Jagadguru Sri Shivarathreeshwara Medical College, Jagadguru Sri Shivarathreeshwara University, Mysore, IndiaAbstract: In sickle cell disease (SCD), the clinical manifestations are due to episodes of vascular occlusion and haemolysis. Most of the children experience vaso-occlusive pain episodes by the age of six years. Renal injury in sickle cell disease referred to as sickle cell nephropathy is a frequent yet under-recognised complication. Renal papillary necrosis (RPN) as the first presentation in SCD is rare. We are reporting a 12 year old child with no prior vaso-occlusive episodes, presenting with renal papillary necrosis due to Sickle Beta and Thalassemia.en-USRenal Papillary NecrosisSickle Beta and ThalassemiaSickle Cell DiseaseSickle Cell NephropathyArticle