Khatri, NSKoirala, SAryal, AMaskay, PPaudel, SKarkey, ABaker, SShilpakar, OShrestha, KBasnet, B2026-06-152026-06-152009https://hdl.handle.net/20.500.14572/6511N.S. Khatri Oxford University Clinical Research Unit, Patan Hospital, Lagankhel, Lalitpur, Kathmandu, Nepal S. Koirala Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal A. Aryal Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal P. Maskay Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal S. Paudel Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal A. Karkey Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal S. Baker Patan Hospital, Lagankhel, Lalitpur, Bagmati, Kathmandu, Nepal O Shilpakar Oxford University Clinical Research Unit, Hospital for Tropical Diseases,Ho Chi Minh City, Viet Nam K. Shrestha Oxford University Clinical Research Unit, Patan Hospital, Lagankhel, Lalitpur, Kathmandu, Nepal B. Basnet Oxford University Clinical Research Unit, Patan Hospital, Lagankhel, Lalitpur, Kathmandu, NepalAbstract Salmonella Typhi is a causative agent of enteric fever, which is an ongoing public health problem in urban areas of the Kathmandu valley in Nepal. It is estimated that approximately 5 % of people in an endemic enteric fever area may asymptomatically carry Salmonella Typhi in the gall bladder. Here we describe a rare clinical manifestation of chronic Salmonella carriage. A 40 year old male resident of Kathmandu underwent an emergency cholecystectomy for acute cholecystitis and gall bladder perforation. No stone was identified but Salmonella Typhi was cultured from the gall bladder. Keywords: Acalculous cholecystitis, perforation, Salmonella Typhien-USAcalculous cholecystitisperforationSalmonella TyphiArticle