Keyal, Niraj KumarSingh, AmitPokhrel, AbishekBhujel, AmidChaurasia, Rupesh Kumar2026-02-122026-02-122021https://hdl.handle.net/20.500.14572/4707Niraj Kumar Keyal Department of Critical Care Medicine, B &C Medical College Teaching Hospital & Research center, Birtamod, Jhapa, Nepal https://orcid.org/0000-0001-8587-1718 Amit Singh Department of General Surgery, B &C Medical College Teaching Hospital & Research center, Birtamod, Jhapa, Nepal Abishek Pokhrel Department of Radiology, B &C Medical College Teaching Hospital & Research Center, Birtamod, Jhapa, Nepal https://orcid.org/0000-0001-7855-1636 Amid Bhujel Department of Critical Care Medicine, B &C Medical College Teaching Hospital & Research center, Birtamod, Jhapa, Nepal https://orcid.org/0000-0003-0513-684X Rupesh Kumar Chaurasia Department of Critical Care Medicine, B &C Medical College Teaching Hospital & Research center, Birtamod, Jhapa, Nepal https://orcid.org/0000-0002-1560-2034Abstract: Severe acute alcoholic pancreatitis is a second common form of pancreatitis that requires intensive care unit care and has high morbidity and mortality due to lacking specific treatment. Management of alcoholic pancreatitis is generally non- specific and supportive. We hereby present a case-series of three patients that describes the successful treatment of severe acute alcoholic pancreatitis with ulinastatin and other supportive treatment. From this we want to emphasize that ulinastatin a protease inhibitor can be used in the treatment of alcoholic pancreatitis.en-USalcoholicantiproteasespancreatitisArticle