Karki, DikshaAdhikari, PurbeshShrestha, DiptiKafle, Anil2026-03-162026-03-162021https://hdl.handle.net/20.500.14572/5147Diksha Karki Department of Pathology, BP Koirala Institute of Health Sciences, Dharan, Nepal https://orcid.org/0000-0002-5399-2029 Purbesh Adhikari Department of Pathology, BP Koirala Institute of Health Sciences, Dharan, Nepal https://orcid.org/0000-0001-6278-7855 Dipti Shrestha Department of Pathology, BP Koirala Institute of Health Sciences, Dharan, Nepal Anil Kafle Department of Pathology, BP Koirala Institute of Health Sciences, Dharan, NepalAbstract: Colon carcinoma spreads locally around the intestine wall and can undergo distant metastasis via the hematogenous or lymphatic spread. It rarely metastasizes to the female genital tract and is not fully reported to involve a uterine leiomyoma. Herein we report such an unusual case of a 27 years female a known case of sigmoid colon adenocarcinoma who presented with abdominal pain with bilateral adnexal mass and per vaginal bleeding. Exploratory laparotomy with bilateral resection of ovaries with subsequent polypectomy was done, which on histopathology, it revealed metastatic adenocarcinoma in bilateral ovaries and submucosal leiomyoma. Hence, a lesion with dimorphic histomorphology should be carefully evaluated to rule out the possibility of malignant-to-benign tumor-to-tumor metastasis.en-USadenocarcinomacase reportmetastasisuterine leiomyomaArticle