Publication:
Neonatal Screening for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Eastern India

Simple item page
creativeworkseries.issnISSN 1990-7974 eISSN 1990-7982
dc.contributor.authorMukherjee, Sweta
dc.contributor.authorMallige, Ashish
dc.contributor.authorChowdhry, Anupama
dc.contributor.authorDevgan, Amit
dc.contributor.authorSingh, Brajesh
dc.contributor.authorMukherjee, Bhasker
dc.contributor.authorShaw, Subhash Chandra
dc.date.accessioned2025-11-26T09:52:55Z
dc.date.available2025-11-26T09:52:55Z
dc.date.issued2021
dc.descriptionSweta Mukherjee Department of Paediatrics, Armed Forces Medical College, Pune, India Ashish Mallige Department of Paediatrics, Command hospital (EC), Kolkata, India Anupama Chowdhry Department of Physiology, Ex-Army College of Medical Sciences, New Delhi, India Amit Devgan Department of Paediatrics, Armed Forces Medical College, Pune, India Brajesh Singh Department of Pathology, Command Hospital (EC), Kolkata, India Bhasker Mukherjee Department of Biochemistry, Armed Forces Medical College, Pune, India Subhash Chandra Shaw Department of Paediatrics, Armed Forces Medical College, Pune, India
dc.description.abstractAbstract: Introduction: The overall magnitude of the frequency of G6PD deficiency ranges between 0 to 10 percent in the Indian population. This prospective study was planned to estimate the prevalence of G6PD deficiency in newborn population born in a tertiary care centre in Eastern India. Methods: This prospective observational study was undertaken among all consecutively delivered neonates born in a tertiary care teaching hospital of Eastern India, between Apr 2016 and Oct 2017. Prematurity less than 32 weeks and perinatal asphyxia requiring extensive resuscitation were excluded from the study. Umbilical cord blood samples were collected in a EDTA containers, drawn from the placental side of the umbilical cord incised while severing it at the time of birth. The G6PD levels were estimated quantitatively based on ultraviolet (UV) method by quantitative sphectrophotometric assay using ILab 650 fully automated analyzer. All babies wherein the cord blood G6PD levels was less than 6.95 mU/g of Hb was taken as deficient. Results: Mean (SD) of G6PD at birth was 12.56 (3.45) mU/g of Hb. Out of 1037 neonates, five were found to be G6PD deficient. There was increased incidence of neonatal jaundice requiring phototherapy in G6 PD deficient neonates, and it was statistically significant. Conclusion: The prevalence of G6PD deficiency was 0.48% in term and late preterm neonates as assessed quantitatively in cord blood
dc.identifierhttps://doi.org/10.3126/jnps.v41i3.37153
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3284
dc.language.isoen_US
dc.publisherNepal Paediatric Society (JNPS)
dc.subjectNeonatal screening
dc.subjectEastern India
dc.subjectG6PD deficiency
dc.titleNeonatal Screening for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Eastern India
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage412
oaire.citation.startPage408
relation.isJournalIssueOfPublication0b99c152-1968-4a9d-81aa-91bd247df181
relation.isJournalIssueOfPublication.latestForDiscovery0b99c152-1968-4a9d-81aa-91bd247df181
relation.isJournalOfPublication6f9be05c-05a9-4a3e-a5b5-a19a15ab042c

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
408-412.pdf
Size:
407.63 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.86 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

Publications

Connect with us

Nepal Health Research Council © 2023
Ramshah Path, Kathmandu Nepal P.O.Box 7626