Publication: Effect of Single Dose Intramuscular Methylprednisolone Injection into the Masseter Muscle on the Surgical Extraction of Impacted Lower Third Molars: a Randomized Controlled Trial
Files
Date
2014
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Lower impacted third molar surgical extraction usually causes post-surgical sequelae
like pain, trismus and swelling as a result of postoperative inflammatory response.
Objective
The aim of this study was to evaluate and compare the efficacy of single dose
40-mg (1cc) of methylprednisolone acetate, injected into the masseter muscle,
preoperatively one hour before the surgery or post-operatively, immediately
following the surgical removal of impacted lower third molars, in controlling most
common postoperative sequelae, i.e. trismus, pain and swelling of facial soft tissue.
Methods
A randomized control study was done of 60 patients. Each patient was categorized in
two groups, group I and group II, according to the time of receiving methylprednisolone
acetate. Group I was injected 40mg of methylprednisolone acetate into the
masseter muscle via the intrabuccal approach, one hour before the surgery. Group
II was injected 40mg of methylprednisolone acetate into the masseter muscle via
the intrabuccal approach, immediately after suturing of the surgical wound. The
washout period was one month after the first operation. Evaluation were made of
postoperative pain, trismus and swelling. The numeric pain scale (NPS) was used for
pain assessment.
Results
When the patients were administered methylprednisolone acetate preoperatively,
showed superior results in terms of oral aperture, pain and all the facial swelling
parameters, with statistically significant differences versus the postoperatively
administered methylprednisolone acetate (p < 0.05).
Conclusions
A single dose of 40 mg (1cc) methylprednisolone acetate injected into the masseter
muscle preoperatively is more effective in reducing pain, trismus and swelling, when
compared to that administered postoperatively.
KEY WORDS
Impacted lower third molars, intramuscular injection, masseter muscle,
methylprednisolone
Description
Vyas N,1 Agarwal S,1 Shah N,1 Patel D,1 Aapaliya P2
1Department of Oral and Maxillofacial Surgery
Ahmedabad Dental College and Hospital Gujarat, India
2Department of Public Health Dentistry, Pacific
Dental College and Hospital Rajasthan, India