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Epidemiological Characteristics of Hepatitis C Patients Attending a Tertiary Care Hospital

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creativeworkseries.issn1999-6217
dc.contributor.authorKattel, Hari Prasad
dc.contributor.authorSharma, Sangita
dc.contributor.authorAlfsnes, Kristian
dc.contributor.authorPathak, Rahul
dc.contributor.authorRijal, Komal Raj
dc.contributor.authorGhimire, Prakash
dc.contributor.authorAndreassen, Ashild K
dc.contributor.authorBanjara, Megha Raj
dc.date.accessioned2025-07-20T08:10:34Z
dc.date.available2025-07-20T08:10:34Z
dc.date.issued2024
dc.descriptionHari Prasad Kattel Central Department of Microbiology, Kathmandu, Nepal Sangita Sharma Tribhuvan University Teaching Hospital, Kathmandu, Nepal Kristian Alfsnes Norwgian Institute of Public Health, Norway Rahul Pathak Tribhuvan University Teaching Hospital Komal Raj Rijal Central Department of Microbiology, Kathmandu, Nepal Prakash Ghimire Central Department of Microbiology, Kathmandu, Nepal Ashild K Andreassen Norwgian Institute of Public Health, Norway Megha Raj Banjara Central Department of Microbiology, Kathmandu, Nepal
dc.description.abstractBackground: Hepatitis C infection is a major public health concern in Nepal. Epidemiological information on hepatitis C virus along with the status of co-infection with hepatitis B virus and human immunodeficiency virus is essential to controlling the hepatitis C burden. The objective of this study was to determine the sero-prevalence of hepatitis C virus infections, proportions of co-infections with human immunodeficiency virus and hepatitis B virus, and identify the demographic characters, and routes of transmission. Methods: A cross-sectional study was conducted from December 2019 to February 2024 at Tribhuvan University Teaching Hospital. The serological tests were performed by enzyme-linked immunosorbent assays from 25133 patients’ serum in four years. Results: The sero-prevalence of hepatitis C virus -infected patients was 0.8% (211/25133). Among them, 6.6% (14/211) were co-infected with human immunodeficiency virus and 1.4% (3/211) with hepatitis B virus. Among 211 hepatitis C virus patients, 174 (82.5%) were male, 156 (73.9%) were young aged 15–47 years with various professions, 167 (79.1%) were literate, and almost one-third of the patients (33.2%, 70/211) were regular alcoholics. Needle sharing among intravenous drug users (45.5%, 96/211) and sexual intercourse (28%, 59/211) were the most common modes of transmission. Conclusions: Although the prevalence of hepatitis C infections is less than 1%, it is more common among young male intravenous drug users. Awareness of the spread of hepatitis C infections among this population needs to be emphasized to control hepatitis C in Nepal. Keywords: characters; co-infection; hepatitis C, sero-prevalence.
dc.identifierhttps://doi.org/10.33314/jnhrc.v22i03.5308
dc.identifier.urihttps://hdl.handle.net/20.500.14572/424
dc.language.isoen_US
dc.publisherNepal Health Research Council
dc.titleEpidemiological Characteristics of Hepatitis C Patients Attending a Tertiary Care Hospital
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage615
oaire.citation.startPage608
relation.isJournalIssueOfPublicationbdc38a4e-8fed-4c8d-ae10-a4918d68512e
relation.isJournalIssueOfPublication.latestForDiscoverybdc38a4e-8fed-4c8d-ae10-a4918d68512e
relation.isJournalOfPublication40bd2739-8b19-447c-be60-723a1bdd1dcd

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