Publication: Phenytoin Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare and potentially fatal adverse effect characterized by a skin rash with visceral involvement and haematological abnormalities. This adverse drug effect is often misdiagnosed and under-reported especially in paediatric age group due to its rarity and high occurrence of skin rash in various other viral illnesses of children. We report a case of DRESS in a three months old male child. A high index of suspicion, rapid diagnosis and prompt withdrawal can be life-saving for the patient.
Description
NK Natt
Senior Resident, Department of Pharmacology, Government Medical College, Amritsar
S Tarsem
Assistant professor, Department of Paediatrics, SGRD Institute of Medical Sciences and Research, Vallah
Dr Anuba
Junior Resident, Department of Paediatrics, SGRD Vallah, Amritsar
S Simarjeet
Junior Resident, Department of Paediatrics SGRD Vallah, Amritsar
M Sharma
Junior Resident, Department of Paediatrics SGRD Vallah, Amritsa
S Harmanjit
Senior Resident, Department of Pharmacology, All India Institute of Medical Sciences, Delhi
Keywords
Adverse effect, Skin rash, Visceral involvement