Publication:
Intravenous Lipid Emulsion Therapy: A Crucial Approach for Treating Lipophilic Drug Poisoning- A Case Study from Nepal

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creativeworkseries.issnISSN 2822-1893 eISSN 2822-2016
dc.contributor.authorPoudel, Saroj
dc.contributor.authorKhanal, Kishor
dc.contributor.authorGhimire, Anup
dc.contributor.authorShrestha, Pallawi
dc.contributor.authorRijal, Bishakha
dc.contributor.authorShrestha, Aastha
dc.contributor.authorShyaka, Selika
dc.contributor.authorShrestha, Akchhyeta
dc.contributor.authorBikram, Yogesh
dc.date.accessioned2026-02-02T05:23:26Z
dc.date.available2026-02-02T05:23:26Z
dc.date.issued2024
dc.descriptionSaroj Poudel Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Kishor Khanal Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Anup Ghimire Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Pallawi Shrestha Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Bishakha Rijal Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Aastha Shrestha Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Selika Shyaka Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Akchhyeta Shrestha Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal Yogesh Bikram Department of Critical Care Medicine, Nepal Mediciti, Patan, Nepal
dc.description.abstractAbstract: Intravenous lipid emulsion (ILE) therapy has emerged as a promising treatment for lipophilic drug poisoning, particularly in cases where conventional therapies fail. This case study from Nepal highlights the successful use of ILE therapy in treating a severe calcium channel blocker (CCB) overdose. A 37-year-old female patient with an intentional amlodipine overdose presented with bradycardia, hypotension, and metabolic acidosis. Despite initial treatment with high-dose insulin, calcium gluconate, and inotropic support, her condition remained critical. The initiation of ILE therapy led to rapid hemodynamic stabilization, allowing the discontinuation of vasopressors and normalization of metabolic parameters within 24 hours. The patient recovered without adverse effects and was discharged in stable condition. This case underscores the potential of ILE therapy as a life-saving intervention in severe CCB toxicity and highlights the need for further research to optimize its use in clinical practice.
dc.identifierhttps://doi.org/10.3126/nrj.v3i2.83171
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4433
dc.language.isoen_US
dc.publisherNepalese Respiratory Society
dc.subjectIntravenous Lipid Emulsion Therapy
dc.subjectlipophilic drug poisoning
dc.subjectcalcium channel blockers
dc.subjectIntensive Care Unit
dc.titleIntravenous Lipid Emulsion Therapy: A Crucial Approach for Treating Lipophilic Drug Poisoning- A Case Study from Nepal
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage40
oaire.citation.startPage35
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relation.isJournalIssueOfPublication.latestForDiscoveryd4fa4b54-5336-4ae9-8284-585ee744eae5
relation.isJournalOfPublication91ea7cc8-46b2-4796-94bd-2998c28b5ebb

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