Browsing by Author "Adhikari, Deepak"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Publication High-Resolution Computed Tomography (HRCT) Chest Findings in Active Pulmonary Tuberculosis(Nepalese Respiratory Society, 2025) Adhikari, Deepak; Raut, Yuvaraj; Poudel, Dipesh; Paudel, Bigyan; Bhatt, Manali; Adhikari, ShitalAbstract: Background: Tuberculosis (TB) is an airborne infection caused by the acid-fast bacillus Mycobacterium tuberculosis. It is estimated that about 10.8 million people fell ill with tuberculosis worldwide, and about 1.25 million of them died in 2023. In Nepal, nearly half of the population are estimated to harbor latent TB. Early diagnosis and effective treatment are the mainstay of the control of tuberculosis. Objective: This study aimed to evaluate the diagnostic utility of high-resolution computed tomography (HRCT) of the chest in detecting active pulmonary tuberculosis (PTB). Methods: It is a case-control study done in the Department of Radiodiagnosis at Chitwan Medical College, Teaching Hospital from August 2022 to January 2023. Adult patients with presumptive pulmonary TB who underwent both microbiological testing for Mycobacterium tuberculosis, and High-Resolution CT (HRCT) chest imaging were included. Patient’s demographics, clinical features, sputum microscopy for acid-fast bacilli (AFB), GeneXpert for MTB, and relevant HRCT chest findings were recorded in a predesigned proforma. Data were entered into Microsoft Excel and analyzed using IBM SPSS version 20.0. Results: Data from 72 patients with active pulmonary TB were analyzed. Of these, 46 patients (63.9%) had Mycobacterium tuberculosis identified via AFB staining, while the remaining 26 (36.1%) were diagnosed using GeneXpert. The control group included 35 sputum-negative cases where bacteria could not be isolated using GeneXpert. The mean age of patients was 56 years, and the majority were male (68.1%). The most frequent HRCT findings in active TB cases included tree-in-bud appearance (69.4%), enlarged mediastinal lymph nodes (65.3%), and consolidation (56.9%). The tree-in-bud pattern was significantly more common in TB-positive patients compared to controls. Conclusion: Common HRCT chest findings in pulmonary tuberculosis were tree-in-bud appearance, mediastinal lymphadenopathy, and consolidation. Tree-in-bud appearance in HRCT was significantly associated with bacteriologically confirmed pulmonary tuberculosis. When microbiological confirmation is delayed or negative, HRCT chest findings can support early initiation of treatment in suspected cases, thereby reducing community transmission and improving patient outcomes.Publication Moderate Hydronephrosis among Acute Ureteral Calculus on Ultrasonographic Imaging in a Tertiary Care Center in Nepal: A Descriptive Cross-sectional Study Authors(Nepal Medical Association, 2021) Paudel, Dipesh; Adhikari, Deepak; Dhakal, Radha DeviAbstract: Introduction: Ureteric calculi are lying at any point of ureter from the pelvic ureteric junction to the vesicoureteral junction. If left untreated, ureteropelvic junction obstruction can lead to hydronephrosis. With the improved availability of computed tomography and ultrasound scanning, hydronephrosis is being diagnosed more frequently. The main aim of this study is to find out the prevalence of moderate Hydronephrosis among ureteral calculus on ultrasonography imaging in a tertiary care center of Nepal. Methods: A descriptive cross-sectional study was conducted among 110 acute ureteral calculus cases at Radiodiagnosis and Imaging Department of Chitwan Medical College and Teaching Hospital, Bharatpur from 15th August 2020 to 15th May 2021. The ethical approval was taken from the Institutional Review Committee of same institution. Convenient sampling technique was used to select the participant. . The collected data was entered in excel 16 and analysed in Statistical Package for Social Sciences. Point estimate at 95% Confidence Interval was done and frequency and percentage were calculated Results: Out of the 110 cases of acute ureteral calculus, 31 (28.2%) (19.79-36.60 at 95% Confidence Interval) has moderate hydronephrosis in the ultrasonographic imaging. The mean age of participants was 31.61±8.51 years and male to female ratio was 1.97:1. Vesicoureteric junction was the most common site for ureteric calculus 39 (35.5%). Conclusions: The ultrasound is an easy method to be applied, and a fast one to help and diagnose obstructive hydronephrosis. The main causes of hydronephrosis are kidney stones, followed by ureteral stones, with a moderate degree of hydronephrosis.