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NepMed is a Nepal MEDLINE(Medical Literature Analysis and Retrieval System Online) by Nepal Health Research Council(NHRC). It includes bibliographic information for articles from academic biomedical journals covering medicine, dentistry, nursing, pharmacy, dentistry veterinary medicine, and allied health sciences.

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Article

Clinicopathological study of helicobactor pylori infection and gastric carcinoma at a Tertiary Care Hospital in Kathmandu

(Nepal Medical College Pvt. Ltd., 2024) Pathak, Rakesh; Pudasaini, Sujata; Basnet, Manjila

Abstract: Urinary calculi are important problem in urology field. Ureteral stones can cause obstructive uropathy and subsequent deterioration of renal function. The minimal invasive approaches become the major source of treatment modalities with the development of lithotripsy technology. A prospective cross sectional hospital study was conducted in the Urology Department of a tertiary care hospital in Kathmandu for a period of one year (September 2022 to August 2023). A total of 118 patients attending Urology OPD and undergoing laser lithotripsy were included in the study. Ureteroscopic procedure was done using a 6.5 Fr (Wolf Inc., Germany) semirigid ureteroscope under direct endoscopic vision and once the stone was visible, fragmentation was done using Ho-YAG laser. The mean age of the patients was 35.36 ± 11.65 years with male preponderance (58.5%). The common presenting symptom was flank pain and ureteric calculus was more common in the left side (49.2%). Upper ureteric calculus (60.2%) and single stone (83.9%) were more common. Stone size <10 mm (54.2%) and density more than 1000 HU (87.3%) were more common. Stone retropulsion was seen in 16.1% cases and 78% had no post operative complications. SFR in Xray KUB was 94.9% and in USG was 78.8%. The association of SFR in Xray KUB and USG among different variables - male and female patients, patients with stone size < and ≥ 10 mm, stone density < and ≥ 1000 HU and sites (upper, middle and lower) was statistically not significant. The laser lithotripsy technique was found to be effective and safe for ureteric calculus with high SFR.

Article

Laser lithotripsy for the management of ureteric calculus

(Nepal Medical College Pvt. Ltd., 2024) Subedi, Neeraj; Khadka, Mohan; Pun, Hemant; Dhakal, Prakrit; Bogati, Ananya Singh

Article

Evaluation of medical management of phimosis in pediatric patients: a descriptive cross sectional study

(Nepal Medical College Pvt. Ltd., 2024) Bajracharya, Jasmine; Thapa, Bineet; Oli, Kaushal; Lamichhane, Deepika; Shrestha, Rit

Abstract: Phimosis is considered virtually universal in newborn males. Circumcision is mostly done for unresolved phimosis. There is a stream of evidence that suggests steroid cream application is effective in these children prior to any surgical decision. A cross-sectional descriptive study from October 2021 to November 2022, was designed to include all cases of phimosis in male children up to 15 years of age. Caregivers of the patients were counseled and advised for management with hydrocortisone 1.0% ointment twice a daily and follow up in 2 weeks. The resolution rates were noted in 2 weeks and 4 weeks and unresolved children were counseled for either continuation of medical management or circumcision. Electronic registry was used to enroll all the cases and note the outcomes. A total of 146 boys were evaluated. Median age of presentation was 4 years, 113 children (77.4%) were successfully treated with medical therapy and only 33 children (22.6%) had failed medical therapy requiring circumcision. A total of 66 children (58.4%) required only 1 followup for resolution of phimosis. By contrast, 47 children (41.6%) required more than 1 follow-up for resolution. Topical steroid in treatment of phimosis is a very safe, effective, inexpensive and easy approach that attenuates the need for surgical intervention. The response rate is very high and adverse effects are minimal. In the developing world, medical therapy can thus be more feasible of an option as compared to surgery.

Article

Pattern of ABO and Rh blood groups among voluntary blood donors at Nepal Red Cross Society Central Blood Transfusion Service Centre, Kalimati, Kathmandu

(Nepal Medical College Pvt. Ltd., 2024) Singh, Smriti; Katwal, Barsika; Rijal, Tara Devi

Abstract: Blood is a circulatory fluid, responsible for the transport of hormones, nutrients, and enzymes all over the body. It consists of a protein-rich fluid known as plasma, in which are suspended cellular elements: white blood cells (WBC), red blood cells (RBC), and platelets. ABO blood grouping and cross-matching are commonly tested for transfusion of blood and its components, organ transplantation, genetic studies, forensic determinations, as well as for medico-legal issues such as paternity disputes. A descriptive cross-sectional study was conducted in Nepal Red Cross Society Central Blood Transfusion Service Centre, Kalimati, Kathmandu from January 1st 2023 to June 2023 done in 187 donors. Among 187 donors, the age of the donors ranged from 18 years to 55 years, with an average age of 35±0.58 years. The above figure showed that the majority (65.0%) fell into the age group of 26-40 years, followed by those aged 41-55 years, and finally, those aged 18-25 years, respectively. Among all voluntary donors, the majority (71.0%) were male, while 29% were female donors. Data analysis was done by using SPSS and MS-Excel. The result showed maximum number of voluntary donors to be of blood group O, followed by B, A and AB.

Article

Evaluation of effectiveness of sinus surgery in chronic rhinosinusitis patients using sinonasal outcome index-22, modified lund mackay score and rhinosinusitis disability index

(Nepal Medical College Pvt. Ltd., 2024) Pokharel, Apar; Mayya, P Jaya; Bhandari, Chhanya; Sharma, Bibek

Abstract: Functional endoscopic sinus surgery (FESS) is done in patients with chronic rhinosinusitis (CRS) not responding to medical therapy. This study aims to evaluate the subjective, objective and overall quality of life improvement in CRS patients following FESS surgery. Sinonasal outcome index-22, modified Lund-Mackay score and Rhinosinusitis Disability Index were used to evaluate subjective, objective and overall quality of life in patients with CRS. The questionnaires were asked before the surgery and three months after surgery. A total of 110 patients were enrolled in the study. All three types of evaluation showed improvement following FESS surgery. FESS in CRS patients refractory to medical management caused significant improvement in symptom intensity, endoscopic score and overall quality of life.

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