Browsing by Author "Adhikari, Harihar"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Publication A Sinister Disease Hides Behind Recalcitrant Mucocutaneous Disorder(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Adhikari, Harihar; Thapa, Deeptara Pathak; Bhusal, PriyaAbstract: Paraneoplastic pemphigus (PNP) is a rare autoimmune disorder associated with underlying benign or malignant neoplasia. Its signs and symptoms may be the first presentation of a concealed malignancy. Due to late diagnosis, prognosis of PNP is not good, so early diagnosis and treatment is of paramount importance. We present a case of 22 years old female who presented to our out patient department (OPD) with history of recurrent, severe, recalcitrant, painful oral ulcers; lichenoid lesions over the hands and feet and widespread blistering and erosions involving the soles. Histopathological examination was consistent with paraneoplastic pemphigus and showed features of lichenoid dermatitis. CT scan revealed retroperitoneal mass suggestive of Castleman disease. The patient was referred to surgical team for further management.Publication Dermoscopy of Non-Melanocytic Skin Tumors: A Descriptive Study in a Tertiary Care Hospital(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Bhandari, Sajana; Adhikari, Harihar; Joshi, SammiAbstract: Introduction: Dermoscopy is a non-invasive technique that enhances visualization of morphological lesions invisible to naked eye examination and aids in clinical diagnosis. We study its role in non-melanocytic skin tumors. Objectives: The purpose of this study was to evaluate and compare the dermoscopic features of non-melanocyte skin tumors of skin Materials and Methods: A cross-sectional hospital-based study including patients clinically diagnosed as non-melanocytic epidermal tumors was conducted. All dermoscopic findings were studied using a handheld pocket dermoscope (Dermlite DL1) and recorded in a preset proforma. Results: A total of 100 patients were enrolled in the study with mean age of 37 (+/-18.34). There were 56 % females. The face was the commonest site of involvement (56%). Seborrheic keratosis was the commonest clinical diagnosis (55%), followed by pyogenic granuloma 8%, cherry angioma 7%, haemangioma 6%, basal cell carcinoma 5%, achrochordons 4%, xanthelasma, and sebaceous hyperplasia in 3% each. Squamous cell carcinoma and actinic keratosis were seen in 2% each; Angiokeratoma, Bowens disease, stetocytoma multiplex, syringoma, and neurofibroma were all found in 1% of the patients. In dermoscopy, vascular changes were seen in 41% patients, which appeared as regular in 56.1% and rest 43.9% as irregular. Non-vascular changes were seen in 68%. Dermoscopic findings of vascular and non-vascular changes were statistically significantly associated with various types of non-melanocytic epidermal tumors (P <0.05). Conclusion: Our study shows histopathological correlation with the existing dermoscopic characteristics increases the diagnostic accuracy of various non-melanocytic tumors. However, more studies are warranted to statistically prove its utility.Publication Dermoscopy of Psoriasis: A Cross Sectional Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Adhikari, Harihar; Bhandari, SajanaAbstract: Introduction: Dermoscopy is a non-invasive tool that aids in the diagnosis of dermatological diseases. Objectives: The study aims to evaluate the dermoscopic features of psoriasis in the skin. Materials and Methods: All patients clinically diagnosed with psoriasis were enrolled in the study. Dermoscopic findings were studied using a handheld pocket dermoscope (Dermlite DL1) with high magnification. Dermoscopic examination used both polarizing and non-polarizing lenses. Results: The age of the patients ranged from 12 years to 58 years, and the mean age of presentation was 30 years (+/-12.7 years). There were 52% females and 48% males. In dermoscopy, vascular changes were seen in 90%. Vessel arrangement was seen as uniform in 80% of the cases and non-uniform in 20%. Dotted vessels were seen in 88%, glomerular and comma-shaped vessels in 2%. In 94%, white scales were seen, followed by yellow scales in 2% and mixed types in 4%. The background color was red in 68% of cases, pink in 26%, and brownish in 6%. Pigmentary changes were observed in 16%. Follicular changes were observed in 6%. Conclusion: The present study analyzed the characteristic of dermoscopic features in psoriasis. Further studies should be conducted, including inflammatory disorders and their correlation with dermoscopic features.