Browsing by Author "Adhikari, Prabin"
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Publication Diabetes Mellitus among Patients with Non-alcoholic Fatty Liver Disease Visiting the Outpatient Department of Internal Medicine in a Tertiary Care Centre(Nepal Medical Association, 2023) Adhikari, Prabin; Oli, Kaushal; Shrestha, SaloniAbstract Introduction: Diabetes mellitus is a chronic metabolic illness which is mainly associated with reduced physical activity and obesity. Diabetes mellitus and non-alcoholic fatty liver disease may coexist and synergistically lead to poor clinical outcomes. The aim of the study was to find out the prevalence of diabetes mellitus among patients with non-alcoholic fatty liver disease in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among patients with non-alcoholic fatty liver disease in the outpatient department of Internal Medicine of a tertiary care centre between 1st January 2022 and 29th June 2023. Convenience sampling was done. A convenience sampling technique was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 150 patients with non-alcoholic fatty liver disease, diabetes mellitus was seen among 18 (12%) (6.80-17.20, 95% Confidence Interval). Diabetes mellitus was more prevalent in males 12 (66.67%) in patients with non-alcoholic fatty liver disease. Conclusions: The prevalence of diabetes mellitus among patients with non-alcoholic fatty liver disease was found to be lower as compared to similarly reported research studies.Publication Subclinical Hypothyroidism among Patients with COVID-19 Infection in a Tertiary Care Centre: A Descriptive Cross-sectional Study(Nepal Medical Association, 2023) Adhikari, Prabin; Singh, RasuAbstract Introduction: Hypothyroidism occurs as a consequence of chronic autoimmune inflammation of the thyroid gland, which occurs due to the reduced function in the secretion of thyroid hormones. The coronavirus disease infection has shown many complications in all organic systems, during the acute phase of infection and in the post-COVID-19 period. SARS-CoV-2 may induce thyroid dysfunction that is usually reversible, including subclinical and atypical thyroiditis. The aim of this study was to find out the prevalence of subclinical hypothyroidism among patients with COVID-19 infection in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted in the Department of Internal Medicine of a tertiary care centre from 1 September 2022 to 28 February 2023 after obtaining ethical approval from the Research and Institutional Review Committee (Reference number: 15-079/080). Convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 38 patients with COVID-19, subclinical hypothyroidism was seen among 23 (60.53%) (44.99-76.07, 95% Confidence Interval). Conclusions: The prevalence of subclinical hypothyroidism among COVID-19 patients was found to be similar to other studies done in similar settings.