Browsing by Author "Anjum, Md Firoz"
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Publication Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report(Nepal Medical Association, 2023) Anjum, Md Firoz; Twanabasu, Sajal; Shrestha, Sailesh; Lama, Tashi Anjuk; Magrati, DipendraAbstract Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children. It occurs due to autoantibody against glomerular basement membrane collagen and is characterized by rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. As the literature on anti-glomerular basement membrane disease is limited from our part of the world, it is important to consider it as the rare cause of rapidly progressive glomerulonephritis as early intervention improves prognosis. We report a case of a 10-year-old male who initially presented with glomerulonephritis and later was diagnosed with anti-glomerular basement membrane disease.Publication Causes of Mortality in Low Birth Weight Babies at a Tertiary Care Hospital(Nepal Paediatric Society (JNPS), 2021) Sharma Chalise, Shiva Prasad; Mishra, Santosh Kumar; Kasakar, Prerana; Anjum, Md FirozAbstract: Introduction: Decreasing the neonatal mortality has been a major concern to decrease under five mortality rate. Low birth weight (LBW) and prematurity related deaths account to significant percentage of all neonatal deaths worldwide. Causes of mortality in LBW babies are not well documented. Hence this study aims to determine the causes of neonatal mortality among the LBW babies at Patan Hospital, Nepal. Method: It was a retrospective observational study done at the Department of Paediatrics, Patan Hospital, Lalitpur, Nepal. The study period was three years from April 2017 to March 2020. All LBW babies born within the study period were included. Perinatal audit and case records were reviewed and necessary data was extracted. Results were analyzed using appropriate tools. Results: Total LBW babies were 3028 which was 13% of all live births. Deaths among LBW were 83 comprising mortality rate of 26.7 per thousand live births. Among all neonatal deaths 76% of the deaths were LBW babies. Sixty very LBW babies died which contributed to 55% of total neonatal deaths. Mean birth weight was 1185 grams, median 1045 with standard deviation 571 with range of 500 to 2484 grams. Respiratory distress syndrome (35%), sepsis (29%), congenital anomalies (23%) and birth asphyxia (12%) were the most common causes of mortality. Conclusions: Respiratory distress syndrome and sepsis were the most common causes of neonatal mortality among LBW babies. Improved neonatal care with special focus to very and extremely LBW babies might help reduce neonatal mortality.