Browsing by Author "Balhara, Kirtika"
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Publication Predictive Value of Umbilical cord Blood Albumin in early Identification of Neonatal Hyperbilirubinemia: An Observational Study(Perinatal Society of Nepal (PESON), 2025) Singh, Priyamvada; Balhara, Kirtika; Antil, Parveen; Kapoor, Satya KiranAbstract: Introduction: Neonatal hyperbilirubinemia (NH) clinically presents as yellowish discoloration of the skin and sclera. The anticipation of jaundice through the evaluation of cord albumin aims to identify infants at risk of neonatal hyperbilirubinemia promptly, allowing for early intervention to mitigate the potential for bilirubin-induced brain damage. Methodology: A total of 266 eligible neonates were enrolled in the study.Cord albumin samples of neonates were categorized into three distinct study groups based on cord blood albumin levels: group A (CBA <2.8g/dl), group B (CBA-2.8-3.3g/dl) and group C (CBA >3.3g/dl).All neonates (except excluded babies) were followed starting at 24 hours till 72 hours. If Kramer's score exceeded zone 2 on day 1 or zone 3 on day 2/day3 of birth then 1ml of peripheral venous blood was collected and sent for serum bilirubin estimation. Results: On day 2, 30 neonates out of 31 in group A, 25 out of 28 in group B and 3 out of 141 in group C needed phototherapy. On day 3, 8 neonates out of 31 in group A, 1 out of 28 in group B and none of the babies in group C needed phototherapy.In group A, 1 out of 31 neonates needed double volume exchange transfusion on day 3 of life and none of the neonates in group B and C needed exchange transfusion. Conclusion: This study demonstrates cord blood albumin levels as a prognostic indicator for estimation of serum bilirubin which allows a more tailored approach to neonatal care.