Browsing by Author "Bhatta, Sabitri"
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Publication Prediction and Estimation of Postoperative Refractive Error in Phacoemulsification: Using Ultrasound A-Scan and Intra Ocular Lens Master(Nepal Health Research Council, 2024) Bhatta, Sabitri; Joshi, Sagun Narayan; Thapa, Madhu; Awasthi, Suresh; Shrestha, Gauri Shankar; Joshi, Niraj DevBackground: This study aims to predict and estimate the postoperative refractive outcome in participants undergoing phacoemulsification using IOL Master and A-scan biometry. Methods: A cross-sectional study was done where ninety eyes of 90 participants undergone phacoemulsification using SRK/T formula were included in longitudinal research. Each participant underwent axial length (AL) measurement by IOL Master and A-scan, and keratometry reading (k- reading) by manual TOPCON keratometer and automated keratometer on IOL master for IOL power calculation. All the pre-operative measurements between A-scan and IOL master and two keratometers were compared using paired-t tests. The four-week postoperative refractive error was estimated using univariate analysis and its prediction was compared with the ocular biometry parameters using quadratic regression. Results: Preoperative findings were higher for AL and ACD by IOL master and A-scan (0.27±0.14mm; p<0.001, 0.14±0.31mm, p<0.001) respectively. The AL and K-reading were found to be strong predictors of IOL power calculation (? = -1.07; p<0.001, ? = 0.75; p<0.001), respectively. The AL, K-reading were found to be strong predictors for four-week postoperative refractive error (? = -1.563; p = 0.012, ? = 1.052; p = 0.012) where postoperative error was found to be higher (F = 7.521, p<0.001) in A-scan than IOL Master. For K-reading, the two keratometer’s and for AL by A-scan and IOL Master’s level of agreement (95% LoA) was comparable (-0.15 to 0.12mm and -0.01 to 0.54mm). Conclusions: IOL Master is more reliable for ocular biometry and minimizes postoperative refractive error. Keywords: Axial length; intraocular lens power; keratometry-reading; refractive error estimation; postoperative refractive error.Publication Visual Field and Optical Coherence Tomography Parameters With and Without Positive Family History of Glaucoma(Nepal Health Research Council, 2023) Bhatta, Sabitri; Awasthi, Suresh; Basnet, Gyan Bahadur; Maharjan, Indra ManAbstract Background: To evaluate the Retinal Nerve Fiber Layer and Ganglion Cell Complex thickness using Spectral Domain Optical Coherence Tomography with and without positive family history of Primary Open Angle Glaucoma and its relation to visual field. Methods: Total 120 eyes with each subjects with positive family history of Primary Open Angle Glaucoma (Group I, n=30) and healthy subjects without positive family history of Primary Open Angle Glaucoma (Group II, n=30) undergone complete ophthalmic evaluation with Retinal Nerve Fiber Layer, Ganglion Cell Complex and VF obtained from Spectral Domain Optical Coherence Tomography RTVue-100 and Humphrey visual field respectively .The measurements were analyzed and compared among two groups using independent-t test by using SPSS version 23.The relationship of Retinal Nerve Fiber Layer with visual field were evaluated with correlation analysis. Results: The Intra Ocular Pressure and vertical Cup Disc Ratio were significantly higher in Group I with mean difference of 2.48±0.43 (p<0.001) and 0.18±0.23 (p<0.001) respectively. The average, superior, inferior, nasal, temporal RNFL and average Ganglion Cell Complex was significantly lower and thinner in Group I with mean difference of -8.53±2.30 µm (p<0.001), -7.35±3.34 µm (p<0.001), -8.52±3.58µm (p<0.001),-11.87±2.24µm (p<0.001), -5.31±1.95µm (p<0.001) and -8.05±1.52µm (p<0.001) respectively. Correlation plot with Retinal Nerve Fiber Layer thickness as predictor of Mean Deviation and Pattern Standard Deviation indicated statistically significant degree of determination in Group I (r=0.455 and r=0.623, p<0.001 and p<0.001). Conclusions: The Optical Coherence Tomography and visual field Parameters are lower in group I and used as an early predictor, diagnosis, monitoring and management. Keywords: Family history; first degree relatives; ganglion cell complex; primary open angle glaucoma; retinal nerve fiber layer.