Browsing by Author "Bhattarai, N"
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Publication Aberrant Shape of the Heart, “Gourd Shaped”: A Rare Case of Localized Constrictive Pericarditis(Kathmandu University, 2024) Rajbhandari, S; Joshi, S; Bhattarai, N; KC, P; Rajthala, P; Khadka, S; Neupane, NP; Aryal, M; Rajlawot, KABSTRACT Calcific constrictive pericarditis results commonly from the tubercular lesions in developing countries. The localized calcifications associated with the calcific constrictive pericarditis on its own is rare and the calcification along the atrioventricular groove distorting the heart to a shape of gourd is extremely rare. We present a case to highlight the importance of the early diagnosis of the condition. We have approached the patient with echocardiography and commuted tomography for the diagnosis and hemodynamic evaluation. Early treatment is equally important for this condition, as the calcific constrictive pericarditis is curable with pericardiectomy. However, there lacks a clear consensus for the pericardiectomy in patients with localized calcification and medical therapy can be initiated. KEY WORDS Constrictive pericarditis, Computed tomography, Echocardiography, PericardiectomyPublication Prevalence of Microalbuminuria in Patients of Essential Hypertension and its Correlation with Left Ventricular Hypertrophy and Carotid Artery Intima‑media Thickness(Kathmandu University, 2022) Pathak, SR; Bhattarai, N; Baskota, D; Koju, RP; Humagain, SABSTRACT Background Urinary albumin excretion has been associated to cardiovascular events and increased mortality in hypertensive patients. There is limited information among Nepalese patients about the implications of microalbuminuria (MA) in the setting of hypertension and potential cardiovascular morbidity. Objective To investigate the prevalence of microalbuminuria in patients with essential hypertension and its connection with left ventricular hypertrophy (LVH) and carotid artery intima-media thickness (cIMT). Method The study involved 80 hypertension individuals in total. All patients in the study had basic biochemical tests, routine urine evaluations, echocardiography, and carotid artery intima-media thickness measurements performed, and the data were analyzed. Result The prevalence of microalbuminuria was present in 37.5% cases of essential hypertension. The mean left ventricular mass index (LVMI) was significantly higher in patients with increased microalbuminuria as compared to patient with normal microalbuminuria. In addition, a significant positive correlation between microalbuminuria and left ventricular hypertrophy was also observed. Furthermore, mean carotid artery intima-media thickness was found to be higher in patients with microalbuminuria (p < 0.001), with 76.7% of the patients with microalbuminuria having elevated mean carotid artery intima-media thickness. The carotid artery intima-media thickness had a positive correlation with both microalbuminuria and left ventricular hypertrophy. Conclusion Microalbuminuria assessment in hypertensive patients is an important test for the evaluation of target organ damage. This study shows that microalbuminuria is common in hypertension patients, particularly those with left ventricular hypertrophy. Microalbuminuria was found to be associated with left ventricular hypertrophy and carotid artery intima-media thickness. KEY WORDS Carotid artery intima‑media thickness, Essential hypertension, Left ventricular hypertrophy, Microalbuminuria