Browsing by Author "Chakraborty, S"
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Publication Evaluation of Risk Factors for Laryngopharyngeal Reflux among Sikkimese Population(Kathmandu University, 2017) Kesari, SP; Chakraborty, S; Sharma, BABSTRACT Background Laryngopharyngeal reflux is a global health problem and is associated with a huge economic burden and decreased quality of life. Studies describing the epidemiology of laryngopharyngeal reflux are sparse in India and south east Asia. This study becomes significant as it is being conducted in Sikkimese population who resides in high altitude have a different lifestyle. Objective To evaluate the risk factors for laryngopharyngeal reflux among Sikkimese origin. Method Patients of Sikkimese origin visiting Ear Nose Throat outpatient department Were administered with validated questionnaire. The patients were further subjected to validate Reflux symptom Index score. Indirect laryngoscopy was performed to calculate reflux finding score. Presence of laryngopharyngeal reflux was identified with patients having reflux symptom index and reflux finding score of greater or equal to 13 or more and 7 or more. Result Out of 200 subjects analysed, there were 77(38.5%) male and 123(61.5%) female. Heartburn and regurgitation were the most common symptom among the masses. Hoarseness and frequent throat clearance were the commonest laryngopharyngeal reflux symptoms. Various risk factors were computed as mentioned in the results column. Conclusion Study on the above mentioned population differed from rest of the country in terms of dietary habits. Fermented food was found to be one of the important risk factor for the development of laryngopharyngeal reflux in the sikkimise population. KEY WORDS Laryngopharyngeal reflux, risk factors, reflux finding score, reflux symptom Index, sikkimese populationPublication Pachydermoperiostosis And An Eyelid Ptosis Associated With Spiky Keratoderma – An Unusual Presentation(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2014) Das, S; Chakraborty, S; Sarkar, NSAbstract: Pachydermoperiostosis, ( PDP), a rare hereditary disorder that is characterized by digital clubbing, pachydermia, subperiosteal new bone formation, associated with pain, polyarthritis, cutis verticis gyrata, seborrhoea and hyperhidrosis. It mainly presents due to disfiguring facial features, widening of the limbs and bone and joint pain. It affects male population predominantly and transmitted as an autosomal dominant trait. There are many constant features associated with it as well as rarer features. Increased proliferation of the fibroblast and dysregulation of matrix protein play a central role in the pathogenesis of the disease. They are diagnosed primarily on clinical and radiological grounds. Histopathology plays a supportive role in the diagnosis. Such a case has to be differentiated from several other conditions like acromegaly, neurofibroma,,myxedema, primary systemic amyloidosis as wel as from other causes of digital clubbing. The case which is described here is a complete form of PDP which is a rare disease reported in Indian context and that too with the a rarer presentation of spiky palmoplanter keratoderma and severe mechanical ptosis leading to severe visual impairment which was corrected after surgical manipulation of the ptosis. Keywords: Keratoderma, Pachydermoperiostosis, Ptosis