Browsing by Author "Chapagain, Subodh"
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Publication Cranial Autonomic Symptoms in Migraine Patient Presenting in the Department of Neurology of a Tertiary Care Center: A Descriptive Cross-sectional Study(Nepal Medical Association, 2024) Rayamajhi, Parash; Bhattarai, Pravesh; Khadka, Janak; Khanal, Sujit; Chapagain, SubodhAbstract Introduction: Cranial autonomic symptoms (CAS) are typically associated with trigeminal autonomic cephalagias (TACs) and are also a part of TACs' diagnostic criteria. However, they have also been commonly reported in migraine patients. This study aimed to find the prevalence of CAS in Migraine patients who presented to the Department of Neurology in a tertiary care center. Methods: This descriptive cross-sectional study was conducted among migraine patients who visited the Department of Neurology of a tertiary care center from September 2023 to December 2023 after obtaining ethical approval from the Institutional Review Committee. Neurologists used ICHD-3 beta criteria to diagnose migraine and the presence of cranial autonomic symptoms in patients with migraine through face-to-face interviews using a structured questionnaire. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 119 migraine patients, at least one cranial autonomic symptom was seen in 76 (63.86%) (55.23-72.51, at 95% Confidence Interval). Lacrimation 34 (44.73%) and conjunctival injection 27 (35.52%) were the two most commonly reported symptoms. Bilateral CAS was present in 60 (78.94%) patients. Conclusions: The prevalence of at least one CAS in migraine patients was found to be similar to other studies done in similar settings.Publication Hashimoto’s Thyroiditis among Patients with Thyroid Disorders Visiting a Tertiary Care Centre(Nepal Medical Association, 2023) Parajuli, Suraj; Bhatt, Navin; Regmi, Anil; Chapagain, Subodh; Panday, Pradumna; Singh, Arjan; Nepal, Shristi; Karki, Pragya; Agrawal, Shweta; Bhattarai, JyotiAbstract Introduction: Hashimoto’s thyroiditis is a chronic autoimmune lymphocytic thyroiditis characterised by thyroid autoantibodies. Early detection and treatment of this condition help in reducing the morbidity and mortality associated with it. The aim of the study was to find out the prevalence of Hashimoto’s thyroiditis among patients with thyroid disorders visiting a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among patients visiting the outpatient department of a tertiary care centre. Data from 14 April 2017 to 13 April 2019 was collected between 30 June 2022 to 15 September 2022 from medical records. Ethical approval was obtained from the Nepal Health Research Council. Hashimoto’s thyroiditis was diagnosed based on clinical presentation and positive antibodies to thyroid antigens. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 813 patients with thyroid disorders, 393 (48.33%) (44.89-51.77, 95% Confidence Interval) had Hashimoto’s thyroiditis. The manifestation of the spectrum of Hashimoto’s thyroiditis were euthyroid in 215 (54.70%), subclinical hypothyroidism in 102 (25.95%), subclinical hyperthyroidism in 23 (5.85%), overt hyperthyroidism in 9 (2.30%) and overt hypothyroidism in 4 (1.02%). Conclusions: The prevalence of Hashimoto’s thyroiditis among patients with thyroid disorders was higher than in other studies done in similar settings.Publication Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report(Nepal Medical Association, 2023) Khanal, Pitambar; Paudel, Sandip; Chapagain, Subodh; Thapa, Saurav; Gyawali, MadanAbstract Sjogren's syndrome is a rare chronic autoimmune disease characterised by dry eyes and dry mouth due to autoimmune destruction of the lacrimal and salivary glands, which can occur concurrently with other autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, or thyroiditis. It can lead to renal complications such as interstitial nephritis and glomerulonephritis, with distal/ type 1 renal tubular acidosis which may result in life-threatening electrolyte imbalance. We present a case of a 35-year-old female who presented with complaints of multiple episodes of muscle weakness. Type 1 renal tubular acidosis was discovered to be the cause of her symptoms which lead to the subsequent diagnosis of Sjogren’s syndrome. This is rare presentation of Sjogren’s syndrome, and it poses a challenge to diagnosis. Early detection and diagnosis of Sjogren's syndrome might be difficult due to existing diagnostic criteria, which contributes to a higher likelihood of missed diagnosis.Publication Overweight among Medical Students of a Medical College(Nepal Medical Association, 2024) Bhattarai, Ashish; Chapagain, Subodh; Shrestha, Saroj; Yadav, Priya; Ratna, BiswashAbstract Introduction: Overweight and obesity are rapidly increasing worldwide, posing a significant global health challenge. Medical students are at a higher risk of developing obesity due to factors such as a sedentary lifestyle, inadequate physical activity, unhealthy eating patterns, elevated stress levels, and the extensive amount of information they need to learn. The aim of this study was to find out the prevalence of overweight among medical students of a medical college. Methods: A descriptive cross-sectional study was conducted among medical students of a medical college from 5 October 2022 to 10 November 2022 after obtaining ethical approval from the Institutional Review Committee. Height in meters and weight in kilograms of students were measured to calculate body mass index. A convenience sampling method was used. The point estimate at a 95% Confidence Interval was calculated. Results: Among 261 medical students, 43 (16.47%) (11.97-20.97, 95% Confidence Interval) were overweight. Among them, 32 (74.41%) males and 11 (25.58%) females were overweight respectively. Conclusions: The prevalence of overweight among medical students is lower than in other studies done in similar settings.