Browsing by Author "Chaudhary, Manoj Kumar"
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Publication An Outbreak Investigation of Mumps in Eastern Nepal – An Observational Study(Nepal Paediatric Society (JNPS), 2024) Chaudhary, Manoj Kumar; Chaudhary, Pankaj; Parajuli, Surya Bahadur; Rimal, Hem SagarAbstract: Introduction: Mumps is an acute viral infection caused by a paramyxovirus. Mumps outbreak has been observed in different parts of the world, recently an outbreak was observed in South Africa on May 2023. Although, Mumps is a vaccine preventable disease it has not been included in the routine immunization schedule of Nepal as well as it does not fall under the category of notifiable disease. Complication of Mumps has been observed from children to adults leading to burden in the family and society. The study was done to investigate the burden of mumps in eastern Nepal from May, 2023 to October, 2023. Method: This was an observational, descriptive study, done in pediatric department of BMCTH from May to October, 2023. 160 children, up to the age of 14 years were clinically diagnosed as Mumps and outbreak was confirmed by PCR testing of Buccal swab. Results: Mumps outbreak peak was observed from May-October, 2023, with the incidence of 160 cases. Affected children were mostly belonging to Morang district (108,68%) followed by Sunsari (43,27%). Incidence of disease occurred mostly in school (129;81%). Most commonly affected children were of age group of 5-9 years. None of the children were vaccinated against mumps. Parotid swelling was the most common presenting complaint which occurred in all children (160;100%) followed by fever (138;86.3%). 104(64.4%) children developed bilateral parotid swelling while (57, 35.6%) children unilateral. Conclusion: Lack of Mumps Vaccination, overcrowding and no event-based surveillance for prompt outbreak detection and response were causes of mumps outbreak. Key words: Mumps; Outbreak; NepalPublication Association of Androgenetic Alopecia with Benign Prostatic Hyperplasia: A Case Control Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2018) Chaudhary, Manoj Kumar; Agrawal, Sudha; Agrawal, Chandra ShekharAbstract Introduction: Androgenetic alopecia (AGA) is associated with increased risk of several systemic diseases and some environmental factors, however, controversies exist. Since AGA and Benign Prostatic Hyperplasia (BPH) share common pathogenesis and AGA manifests some decades before BPH onset, it may serve as an early marker of BPH. Objective: This study was conducted to know AGA and its association with BPH in men ≥20 years of age. Materials and Methods: Clinically diagnosed cases of AGA (n=176) and 117 age matched healthy controls were enrolled. All cases and controls were subjected for abdomino-pelvic ultrasonography, urinary flowmetry, fasting lipid profiles, glycemic index and body mass index. International Prostate Symptom Score (IPSS) was also assessed. Results: Among 176 patients, 120 (68.18%) had Hamilton-Norwood grade III AGA and 56 (31.82%) had grade IV-VII AGA. In both groups, 140 (79.55%) cases and 93 (79.49%) controls were aged <35 years respectively. Family history of AGA was present in 108 (61.36%) cases and 2 (1.71%) controls. This observation was statistically significant with OR= 89.61 (95%CI 23.67-339.29). Three (1.7%) cases and none of the controls had prostate volume >30ml. Seventeen (9.66%) cases and 4 (3.42%) controls were graded as moderately/severely symptomatic IPSS. Statistically significant association was seen between family history and early onset of hair loss (<35 years) in a male sibling or parent. Conclusion: Although positive family history was associated with early onset of AGA, no association between AGA and BPH could be elicited in our study. Keywords: Alopecia, body mass index, glycemic index, lipids, prostatic hyperplasia