Browsing by Author "Das, Niloy Kumar"
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Publication Differentiating Scrub Typhus, Dengue Fever and Typhoid Fever in Indian Children Presenting with Acute Febrile Illness(Nepal Paediatric Society (JNPS), 2020) Chatterjee, Saheli Misra; Mondal, Suman; Mukhopadhyay, Kaushik; Das, Niloy KumarAbstract: Introduction: The disease spectrum of dengue, scrub typhus and typhoid presenting as acute febrile illness is often a diagnostic dilemma to the clinician. The purpose of this study is to compare the clinical features and laboratory parameters of children suffering from typhoid, dengue and scrub typhus and use these parameters in early identification of scrub typhus before conclusion is made from serological diagnosis. Methods: A retrospective observational analytical study was conducted among children presenting with acute febrile illness in a tertiary care level hospital. Over the period of one year 113 cases were identified of which 39 were dengue, 44 were typhoid and 30 were scrub typhus. Results: The mean age of the children was 7.45 ± 2.98 years, median was eight with an interquartile range of six to ten years. The male to female ratio was 1.3:1. Symptoms of vomiting (61.54%), headache (46.15%) and hepatomegaly (47.37%) were significantly higher among children with dengue fever. A significantly higher number of children with scrub typhus fever had temperature above 40°C. The incidence of low haemoglobin, raised C reactive protein, raised ALT and low albumin levels were significantly higher in them. Children with acute febrile illness having temperature > 40°C, absolute neutrophil/lymphocyte ratio > 2 early in the illness were more likely to suffer from scrub typhus with relative probability ratio (RPR) of 25.68 and 10.57 respectively (p < 0.001). Children with WBC < 5000/mm3 were more likely to be suffering from dengue with RPR of 10.60 (p < 0.001). Conclusion: Children with acute febrile illness with temperature > 40°C and absolute neutrophil/lymphocyte ratio > 2 early in the illness were more likely to be suffering from scrub typhus.Publication Neonatal Outcome in Early and Late Gestational Diabetes Mellitus(Nepal Paediatric Society (JNPS), 2017) Misra, Saheli; Das, Niloy KumarAbstract: Introduction: Gestational diabetes mellitus in pregnancy is quite common and the prevalence is higher in ethnic communities. This study aims to look at neonatal complications and NICU admissions occurring in early and late onset gestational diabetes for better monitoring and management of neonatal complications. Material and Methods: This is a prospective observational study in a neonatal intensive care unit of a tertiary hospital in Kolkata over a year. Neonates born to mothers with gestational diabetes were admitted for observation in NICU. Their demographics and complications were noted. Maternal details were collected from maternal records. Results: Gestational diabetes was noted in 45.8% in early pregnancy. 33.3% mothers were managed with insulin. 75% delivered by Ceasarean section. Preterm delivery noted in 23.6%. Complication were 60.60% in early onset gestational diabetes which was significantly greater (p<0.05). Hyperbilirubinaemia and hypoglycaemia were the commonest complication. Macrosomia and congenital complications were seen in early onset GDM. Conclusion: Strict monitoring and intervention is necessary in early gestational diabetes to prevent neonatal complications.