Browsing by Author "Ghosh, A"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Publication A prospective and retrospective study of actinomycosis in last five years at Manipal Teaching Hospital, Pokhara, Nepal(Kathmandu University, 2007) Talwar, OP; Ghosh, A; Pradhan, S; Swami, RM; KC, ShivrajAbstract Objective: The study was carried out to determine the clinical and morphological presentation of actinomycosis and its association with malignancy and other opportunistic infections. Material and Methods: A prospective and retrospective study of cases was done from January 2001 to December 2006 (5 years) in the department of pathology. Result: Total 19 cases of actinomycosis were found during this period. Patients presented with discharging sinus and non-healing superficial abscess. Out of 19 cases, three cases were associated with malignancy, two cases were associated with aspergillosis while one case was clinically misdiagnosed as malignancy. All cases were diagnosed pathologically except a case of maxillary sinusitis which was initially suspected as fungal sinusitis by CT scan. Since actinomycosis is often misdiagnosed it is important to know the clinical presentation and morphological features of actinomycosis for correct management. Conclusion: The clinical features and histopathological findings of actinomycosis are important to understand for its correct diagnosis and better management of patient. Key words: Actinomycosis, fungusPublication Primary tuberculosis of the thyroid gland(Kathmandu University, 2007) Dawka, S; Jayakumar, J; Ghosh, ATuberculosis of the thyroid is rare even where tuberculosis per se is common. We report a case of primary tuberculous goitre in a young man from mid-western Nepal. Key words: thyroid tuberculosis, tuberculous goitre.Publication Tumour and tumour-like conditions of peripheral nerve origin: Ten years’ experience(Kathmandu University, 2010) Ghosh, A; Talwar, OP; Pradhan, SVAbstract Background: There are four major lesions which may arise in the peripheral nerve, namely neuroma, schwannoma, neurofibroma and malignant peripheral nerve sheath tumor. Objective: In the present study we look into the spectrum of peripheral neural tumors including their age distribution site distribution and histopathology. Materials and methods: This is retrospective study conducted in the Dept of Pathology, Manipal Teaching Hospital, Pokhara. All histopathologically diagnosed cases of primary lesions of peripheral nerve during the period Jan 2000 to Nov 2009 were reviewed and the data were analysed. Result: A total of 114 cases of peripheral neural lesions were reported in the same period. Total number of nonmalignant cases was 106 (93%) while malignant cases were 8 (7%). Among the nonmalignant cases neurofiboma was the commonest (51 cases, 45% of all) closely followed by schwannoma (39 cases, 34% of all). Among the neurofibroma cases only 2 cases had multiple neurofibromatosis while others were solitary. Among the schwannoma cases 4 were diagnosed as ancient schwannoma with presence of bizarre cells with hyperchromatic nuclei. The commonest site involved for both schwannoma and neurofibroma was scalp-face-neck followed by back. The age range for schwannoma was 16 to 75 years whereas the same for the neurofibroma cases was 2 to 82 years. MPNST cases were seen in the age range of 40 to 72 with 3 cases in upper extremity, 3 in lower extremity and 1 each in lip and cheek. 1 case was diagnosed as cellular neurofibroma with atypia in tongue and was confirmed by S100. Conclusion The majority of the tumor are benign and the commonest benign tumor was neurofibroma of sporadic type, closely followed by schwannoma. In our study the commonest site was scalp-face-neck unlike other studies. This may be due to more compliance of the patients due to cosmetic reason. Key words : Malignant peripheral nerve sheath tumor, Neurofibroma, Peripheral nerve, Schwannoma,