Browsing by Author "Jha, Anil Kumar"
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Publication Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Pradhan, Susmita; Jha, Krishna; Kumari, Priyanka; Shrestha, Shristi; Jha, Anil KumarAbstract: We describe a case of a 5-year-old boy who presented with multiple mild itchy and painful blisters predominantly over his trunk and limbs for one year with multiple tense bullae with hypopyon signs resulting in a half-and-half appearance of the blisters. A skin biopsy showed subepidermal separation with predominantly neutrophils and eosinophils in the bulla cavity and mixed infiltrate in the papillary dermis. We would like to report a case of chronic bullous disease of childhood and review its differentials for diagnostic approaches to blistering disease in children.Publication Cutaneous Lymphoma in a Tertiary Skin Hospital and Referral Centre in Nepal(Nepal Health Research Council, 2024) Adhikari, Ram Chandra; Shah, Mahesh; Kempf, Werner; Jha, Anil KumarBackground: Primary cutaneous lymphomas are a distinct group of rare lymphoid neoplasms with absence of extracutaneous lymphomas at the time of presentation. They are rare in Nepal and no data on cutaneous lymphoma have been published from this country till date. Methods: This retrospective study included 15 cases of cutaneous lymphomas retrieved from the records of department of Dermatopathology, DI Skin Hospital and Referral Centre, Bansbari, Kathmandu, Nepal. Patients were diagnosed according to the current WHO classification for cutaneous lymphoma. Results: A total of 15 cases were studied with median age of 45 years (range: 22 to 81 years) and male to female ratio of 1.5:1. Primary cutaneous lymphomas constituted 13 cases out of 15 and the most common type of cutaneous lymphoma was mycosis fungoides and variants 5 (33%), followed by CD30 positive primary cutaneous anaplastic large cell lymphoma constituting 2 (13%). T-cell cutaneous lymphoma constituted 13 (87%) and B-cell cutaneous lymphoma 2 (13%). Conclusions: Cutaneous T-cell lymphomas were more frequent than cutaneous B-cell lymphomas in Nepalese patients. Mycosis fungoides and variants are commonest type of primary cutaneous lymphomas. Keywords: Histopathology; mycosis fungoides; primary cutaneous t-cell lymphoma; WHO classification.Publication Quality of life in Patients with Melasma: A Hospital-Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Mainali, Priyanka; Jha, Anil Kumar; Shrestha, Shristi; Thapa, Deeptara Pathak; Joshi, Smita; Amatya, BibushAbstract: Introduction: Melasma is the most common cause of facial melanosis and one of the most common diseases presenting to the Dermatology department. It can lead to psychological and emotional distress for the patients and can hamper their quality of life. So, this study was done to assess the quality of life among patients with melasma so that the need for couseling of these patients could be assessed along with medical treatment. Materials and Methods: This was a hospital based cross sectional study with 205 clinically diagnosed cases of melasma during the study period of one year. Melasma area severity index (MASI) score was recorded for each patient. Melasma quality of life was evaluated using the Melasma related Quality of Life (MELASQOL) score. MASI score and MELASQOL score were correlated using the Chi square test and socio-demographic details were also recorded. Results: The mean MASI score in our study was 14.39 and the mean MELASQOL score was 34.98. The correlation of the MASI score with the MELASQOL score was found to be statistically significant (p value = 0.000). Conclusion: MELASQOL score can be used to assess the quality of life in patients with melasma and the impairment in quality of life depends upon the MASI score.Publication Trichoscopic Study on Tinea Capitis: A Hospital Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Joshi, Anisha; Jha, Anil Kumar; Shrestha, Shristi; Thapa, Deeptara Pathak; Joshi, Smita; Amatya, BibushAbstract: Introduction: Tinea capitis is a common dermatophyte infection of the scalp and hair shaft, most commonly observed in children. Trichoscopy is nonivasive tool which helps in early diagnosis and prompt treatment of tinea capitis. Objectives: This study was carried out with the aim to describe the trichoscopic features of tinea capitis and to find out its different clinical variants with the aid of trichoscopy. Materials and Methods: This is a hospital based cross sectional descriptive study conducted from 1st January 2019 to 31st December 2019. All patients clinically diagnosed with tinea capitis were included in the study. Result: A total of 50 patients with tinea capitis were recruited. The most common age group was found to be 6-10 years (52%) and 27 patients (54%) were female. Majority of the population were students, i.e. 46 patients (92 %). Family history was positive in 38% of cases. The clinical variants seen were black dots in 20 patients (40%), followed by gray patch in 15 patients (30%), kerion in 8 patients (16%) and combined type (both gray patch and black dots) in 4 patients (8%). The most common trichoscopic feature were black dots in 40 (80%), followed by comma hairs in 38 (76%), corkscrew hairs in 33 (66%), and broken hairs in 24 (48%). Conclusion: This study highlighted that the use of trichoscopy as non-invasive tool helped in diagnosing the cases of tinea capitis without the use of wood’s lamp and laboratory investigations.