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Browsing by Author "Jha, Roshan Kumar"

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    Dengue among Patients Visiting Department of Medicine in a Secondary Care Centre: A Descriptive Cross-sectional Study
    (Nepal Medical Association, 2023) Tamang, Basanta; Basnet, Ajaya; Khadka, Sudip; Joshi, Pramod; Jha, Roshan Kumar; Joshi, Rijuta; Rai, Shiba Kumar
    Abstract Introduction: Dengue, caused by the dengue virus, has a wide range of clinical features, including fever, body ache, lethargy, nausea, and vomiting. Blood-based biomarkers in patients with dengue virus infection reflect a variety of clinical spectrums, from bleeding manifestations to liver abnormalities, and can serve as an essential tool for clinicians. This study aimed to determine the prevalence of dengue among patients visiting the Outpatient Department in a secondary care centre. Methods: A descriptive cross-sectional study was conducted among patients visiting the Outpatient Department from 16 May 2022 to 15 November 2022. Ethical approval was obtained from the Institutional Review Committee (Reference number: 20790202). The socio-demographic details and biochemical and haematological findings of dengue virus-infected patients diagnosed with rapid diagnostic tests were collected. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated. Results: Out of 706 individuals, the prevalence of dengue was 83 (11.76%) (9.38-14.14, 95% Confidence Interval). The median age of dengue virus-infected patients was 40 years, and the majority were males 54 (65.06%). Conclusions: The prevalence of dengue was found to be lower than in other studies done in similar settings.
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    Emerging Fungus, Candida auris: A Case Report
    (Institute of Medicine, Tribhuvan University, 2025) Jha, Roshan Kumar; Raut, Shristi; Adhikari, Mahesh; Rai, Junu Richhinbung; Shah, Chhaya; Kattel, Hari Prasad; Sharma, Sangita
    Abstract: Candida auris is a growing fungal threat that has sparked global concern. It has been linked to healthcare-related outbreaks and infections around the world and has been reported in numerous countries. This case report describes an infection caused by Candida auris in a 21-year-old patient with a prolonged hospital stay. On the 60th day of admission, the patient developed persistent fever and cerebrospinal fluid culture revealed Candida spp. Identification of the species and antimicrobial susceptibility testing was done by VITEK-2. The isolate was sensitive to flucytosine and voriconazole and resistant to fluconazole and amphotericin B. Voriconazole was started after the culture and sensitivity results.

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